THE USE OF ATORVASTATIN IN MODERN CARDIOLOGY TO REDUCE THE RISK OF CORONARY HEART DISEASE

A. I.S.
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Abstract

Abstract. This article discusses issues regarding the use of drugs of the statin group for the prevention of diseases of the cardiovascular system, namely the use of atorvastatin in the prevention of coronary artery disease. The study involved 80 patients. at the same time, 65 participants in the study suffered from coronary artery disease, they were diagnosed with angina pectoris of functional class 2, 15 people were potentially healthy, all participants had a common average age and gender characteristics. All patients included in the study were divided into two groups: main and control. The first group received atorvastatin as therapy for IHD, the second group received standard IHD therapy, which included beta-blockers, antianginal drugs, etc. The results of the study were evaluated after 6 weeks and six months. An auxiliary instrumental method was the veloergometric test, as the most optimal option relative to others. This technique was used to verify the ischemic heart disease. To conduct a veloergometric test, the Cardiovit AT-10 apparatus was used, which allows you to gradually increase the load. The study included several stages, each stage assumed a 3-minute load. The load power was determined by a number of factors, such as weight, height of the patient, comorbidities, and age. In the first group, there is a clear positive trend and changes in the lipid profile, which persist for six months. In patients of the second group, such dynamics were not reliably detected. Also, all patients with coronary heart disease underwent a determination of the correspondence of biological age to chronological age. In this case, a formula based on the results of a well ergometric study was used.
阿托伐他汀在现代心脏病学中降低冠心病风险的应用
摘要本文讨论了他汀类药物预防心血管系统疾病的用药问题,即使用阿托伐他汀预防冠状动脉疾病。这项研究涉及80名患者。同时,研究中的65名参与者患有冠状动脉疾病,他们被诊断为功能级2的心绞痛,15人潜在健康,所有参与者都有一个共同的平均年龄和性别特征。所有纳入研究的患者分为两组:主要组和对照组。第一组采用阿托伐他汀治疗IHD,第二组采用IHD标准治疗,包括受体阻滞剂、抗心绞痛药物等。研究结果分别在6周和6个月后进行评估。一种辅助的仪器方法是测速试验,相对于其他方法是最理想的选择。该技术用于缺血性心脏病的诊断。为了进行速度测量测试,使用了心血管AT-10仪器,它允许您逐渐增加负荷。这项研究包括几个阶段,每个阶段的负荷为3分钟。负荷功率由许多因素决定,如患者的体重、身高、合并症和年龄。在第一组中,有明显的积极趋势和血脂变化,持续6个月。在第二组患者中,没有可靠地检测到这种动态。此外,所有冠心病患者都进行了生理年龄与实足年龄的对应测定。在这种情况下,使用了基于井几何研究结果的公式。
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