FUNCTIONAL CONSTIPATION IN CHILDREN : A SYSTEMATIC REVIEW

Yoga Malanda
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Abstract

It is essential to test and diagnose children as soon as possible for functional constipation (FC), which is considered a substantial burden of illness in children. When treated in a timely manner and with the proper medication, babies who have FC have a better chance of making a full recovery. It is estimated that inflammatory bowel disease is responsible for up to 25% of pediatric gastroenterologist visits and 3% of all pediatric outpatient visits globally. It is difficult to estimate the real prevalence of FC in children as a result of the variability of the studies in terms of target population sample, diagnostic criteria, participant ethnicity and environment, technique of data gathering, and lifestyle and psychological characteristics, amongst other considerations. It is possible that the key causes for the worldwide variation in prevalence among studies that have been published are the absence of consensus on diagnostic criteria and cultural variations. Probiotics have the capacity to improve the balance between species, impact intestinal motility by creating lactic acid and short-chain amino acids, and stimulate gut peristalsis by adjusting stool pH. Additionally, probiotics have the potential to increase the number of short-chain amino acids produced in the body. A wide variety of probiotic strains have been the subject of a significant number of investigations. On the other hand, there are not enough evidence available at this time to support the use of probiotics in children who suffer from chronic constipation.
儿童功能性便秘:系统综述
功能性便秘(FC)被认为是儿童疾病的重大负担,尽早对儿童进行检测和诊断至关重要。如果得到及时的治疗和适当的药物治疗,患有FC的婴儿有更好的机会完全康复。据估计,炎症性肠病在全球儿科胃肠病学就诊中占25%,在所有儿科门诊就诊中占3%。由于研究在目标人群样本、诊断标准、参与者种族和环境、数据收集技术、生活方式和心理特征等方面存在差异,因此很难估计儿童FC的真实患病率。在已发表的研究中,患病率在世界范围内存在差异的主要原因可能是对诊断标准和文化差异缺乏共识。益生菌有能力改善物种之间的平衡,通过产生乳酸和短链氨基酸来影响肠道动力,通过调节粪便ph来刺激肠道蠕动。此外,益生菌有可能增加体内产生的短链氨基酸的数量。各种各样的益生菌菌株已经成为大量研究的主题。另一方面,目前还没有足够的证据支持在患有慢性便秘的儿童中使用益生菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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