Estimating the functional age of the cardiorespiratory system

A. Pisaruk, V. Shatilo, I. Antoniuk-Shcheglova, V.Р. Chyzhova, L. Mekhova, S. Naskalova, N. Koshel, S. Ivanov
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引用次数: 1

Abstract

Based on our data on age-related changes in indicators of blood pressure, ECG, HRV, capillaroscopy, and spirography developed a methodology for assessing the biological (functional) age cardiorespiratory system. The study included 116 apparently healthy people aged 20 to 90 years. The formula for calculating functional age was obtained by stepwise multiple regression. Multiple correlation between predicted age and chronological age is large (r = 0.891; p< 0.00001). The mean absolute value of the BA calculation error, in this case, is 6.12 ± 4.36 years. The method developed by us for assessing the functional age of the cardiorespiratory system has sufficiently high accuracy and can be used to assess the risk of developing an age-dependent pathology of the cardiorespiratory system. The implementation of the proposed method will allow not only to identify individuals at risk of developing pathology but also to evaluate the effectiveness of therapeutic, preventive, and rehabilitation measures. Keywords: functional age; cardiorespiratory system
估计心肺系统的功能年龄
基于我们在血压、心电图、HRV、毛细血管镜检查和肺活量描记术等指标中与年龄相关的变化数据,开发了一种评估生物(功能)年龄心肺系统的方法。这项研究包括了116名年龄在20岁到90岁之间看起来很健康的人。通过逐步多元回归得到功能年龄的计算公式。预测年龄与实足年龄的多重相关较大(r = 0.891;p < 0.00001)。本例BA计算误差的平均绝对值为6.12±4.36年。我们开发的评估心肺系统功能年龄的方法具有足够高的准确性,可用于评估心肺系统发生年龄依赖性病理的风险。所提出的方法的实施不仅可以识别有发展病理风险的个体,还可以评估治疗、预防和康复措施的有效性。关键词:功能年龄;心肺系统
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