THE NUMBER OF MAST CELLS AND MACROPHAGES IN CHRONIC GINGIVAL INFLAMMATION IN YOUNG PEOPLE

Abstract

The aim of this work was to study the number of mast cells and macrophages of the gingival lamina propria in young people in chronic inflammation. as a result of the study, new data were obtained on the distribution of mast cells and macrophages in the gum without inflammation. It is for the first time that the effect of microbial inflammation and laser therapy on resident cells of the connective gingival tissue is studied, those cells are part of the oral mucosal immune system, depending on the age. Gingival biopsy material obtained according to dental indications in patients aged 20–40 years was used in the work. CD68+ macrophages were detected by immunohistochemical method, the number and secretory activity of gingival mast cells were evaluated by staining with toluidine blue. The results of the conducted examinations showed that in parodontitis, the number of macrophages and degranulating mast cells in the connective tissue of the gingival lamina propria increases. the use of a diode laser in chronic parodontitis has an effect on the increase in the number of macrophages and gingival mast cells, but not on the degranulation process of mast cells.