DIFFICULTIES IN THE DIAGNOSIS OF COARCTATION OF THE AORTA IN THE NEWBORN IN THE EARLY NEONATAL PERIOD: ANALYSIS OF CLINICAL CASES

M. Gonchar, A. Boichenko, I. Kondratova, B. Ponomar
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Abstract

Introduction. The problem of diagnosing coarctation of the aorta in the early neonatal period is still relevant and presents certain difficulties due to the peculiarities of hemodynamic adaptation to extrauterine life.The aim of the study is to evaluate own clinical observations with emphasis on the difficulty in diagnosing coarctation of the aorta in neonates in the early neonatal period and to perform differential diagnosis with coarctation (pseudocoarctation) of the aorta.The study was carried out according to the ethical norms and principles for conducting medical researches involving human subjects.The research was conducted within the framework of the National Development Program of the Department "Quality of life and course of somatic diseases in children under conditions of social stress", implementation period 2023-2025, state registration number: 0123U101768.Results. The article presents two clinical observations: the first case is a newborn with coarctation of the aorta in a non-emergent state during the first days of life in the presence of evictive morphological changes of the descending aorta; the second case is a newborn with clinical signs of hemodynamic disorders with diagnosed hemodynamic pseudocoarctation (kinking) at the stage of hemodynamic adaptation to extrauterine life. Adequate medical support helps to avoid the development of a serious, potentially dynamic hemodynamic situation.Conclusions. Diagnosis of critical coarctation of the aorta in newborns has certain difficulties associated with the peculiarities of hemodynamics in the early neonatal period and the functioning of fetal communication. In order to avoid mistakes in the diagnosis of the emergency of the defect and to perform timely surgical intervention, dynamic monitoring of blood pressure and saturation indicators of the upper and lower extremities, central hemodynamic parameters is necessary. Differential diagnosis of coarctation of the aorta with kinking (pseudocoarctation) of the aorta should be based on the results of dynamic monitoring of pressure gradient in the descending part of the aorta with control of blood pressure and saturation in the four limbs during the neonatal period.
新生儿早期主动脉缩窄诊断的难点:临床病例分析
介绍。诊断主动脉缩窄的问题,在新生儿早期仍然是相关的,并提出了一定的困难,由于血液动力学的特点适应体外生活。本研究的目的是评估自己的临床观察,重点是在新生儿早期诊断新生儿主动脉缩窄的困难,并对主动脉缩窄(假性缩窄)进行鉴别诊断。这项研究是根据进行涉及人类受试者的医学研究的伦理规范和原则进行的。该研究是在卫生部“社会压力条件下儿童的生活质量和躯体疾病病程”国家发展规划框架内进行的,实施期为2023-2025年,国家登记号码:0123u101768。本文介绍了两个临床观察:第一个病例是新生儿在生命的第一天,在降主动脉形态变化的存在下,主动脉缩窄在非紧急状态;第二例为新生儿,临床表现为血流动力学障碍,在血流动力学适应阶段诊断为血流动力学假性缩窄(扭结)。充分的医疗支持有助于避免发展成严重的、潜在的动态血流动力学情况。新生儿主动脉严重缩窄的诊断有一定的困难,与新生儿早期血流动力学的特点和胎儿沟通功能有关。为避免急诊诊断错误,及时进行手术干预,动态监测上肢、下肢血压、饱和度指标、中心血流动力学参数是必要的。主动脉缩窄合并主动脉扭结(假性缩窄)的鉴别诊断应根据新生儿期主动脉降段压力梯度动态监测结果,同时控制四肢血压和饱和度。
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