Case Report Tuberculosis of The Prostate: Findings of Post Transurethral Resection of Prostate (TURP) Procedure

Kadek Dwi Cahyani, N. Yaniswari, Novitasari Novitasari
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Abstract

Background: Prostate tuberculosis (PTB) is one of extra pulmonary tuberculosis which potentially has more frequent fatal complications and more severe quality of life deterioration. It is a very rare disease, with prevalence of 2.6% of all urogenital tuberculosis (UGTB). Prostate tuberculosis may be a sexually transmitted disease and leads to sexual dysfunction. Case: Male, 54 years old, with urinary retention, dysuria, flank pain in the last 1-month, recurrent urinary tract infection in the past 1 year and decrease body weight of 8 kg in 1 month. Physical examination demonstrates enlarged prostate. Patient was referred to Wangaya Hospital with benign prostate hyperplasia (BPH) and suspect malignancy. After underwent clinical and supporting examination, patient underwent TURP procedure. Histopathology examination revealed PTB. Patient was then treated with first line anti-tuberculosis drug (ATD). Discussion: Multiple risk factors are involved in TB disease. PTB spread occur through hematogenous, lymphatic, or direct routes. Clinical features and supporting examinations of PTB are non-specific. Diagnosis often made through incidental histology finding post TURP. Standard ATD regiment administered based on World Health Organization (WHO) guideline. Duration can be prolonged due to suboptimal concentration to prostate tissue. Conclusion: Multidisciplinary approach for extra pulmonary TB is needed. Thorough history taking, and high index of suspicion are important aspects. PTB diagnosis should be considered in patients with recurrent lower urinary tract symptoms refractory to standard therapy in TB endemic area.
前列腺结核病例报告:经尿道前列腺切除术(TURP)后的发现
背景:前列腺结核(PTB)是一种常见的致命并发症和严重的生活质量恶化的肺外结核。这是一种非常罕见的疾病,患病率为所有泌尿生殖系统结核(UGTB)的2.6%。前列腺结核可能是一种性传播疾病,会导致性功能障碍。病例:男,54岁,尿潴留,排尿困难,近1个月腹痛,近1年复发性尿路感染,1个月体重下降8kg。体格检查显示前列腺肥大。患者以良性前列腺增生(BPH)及疑似恶性肿瘤转诊至旺雅医院。经临床及辅助检查后,患者行TURP手术。组织病理学检查显示为肺结核。患者接受一线抗结核药物治疗。讨论:结核病涉及多种危险因素。肺结核可通过血液、淋巴或直接途径传播。肺结核的临床特征和辅助检查是非特异性的。诊断通常通过TURP后偶然的组织学发现。根据世界卫生组织(WHO)指南实施的标准ATD团。由于对前列腺组织的浓度不理想,持续时间可以延长。结论:需要多学科联合治疗肺结核。详细的历史记录和高怀疑指数是重要的方面。在结核病流行地区,对于复发性下尿路症状难以接受标准治疗的患者,应考虑PTB的诊断。
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