Manufacture of Lyophilized Cortical Bone Particles for Bone Filling Applications by Machining Methods

Abstract

Abstract— Initially was conducted a study of the properties that bone particles for bone filling applications must fulfill and the influence of these properties on the shape and size of the particles. Then we studied the shape and size of commercial particles and determined a geometry that can satisfy these properties with a better assessment than previously studied particles. Then a factorial experiment is design where we studied the parameters that are influential in the process of cutting and the particles that best meet the preselected geometry were selected.