Plateletpheresis: A Comparative Study Between Haemonetics MCS Plus and Spectra Trima

Abstract

Background and Aim: Platelet collection by apheresis techniques has rapidly increased recently owing to its advantages as reduced disease transmission, alloimmunization, in addition to storage characteristics. In this study we compared two apheresis instruments (Haemonetics MCS plus and Spectra Trima) with regard to Platelet (PLT) yield, Collection Rate (CR), White Blood Cell (WBC) and Red Blood Cell (RBC) contamination for selecting equipment for apheresis units. Materials and Methods: Eighty data obtained by Haemonetics MCS plus and Spectra Trima systems (40 for each) were randomly selected among donors attending to the Central blood bank of Ain Shams university for blood donation. Platelet yield/session, number of therapeutic doses, collection rate and WBC/ RBC contamination were recorded for each session. Results: No significant difference was found between 2 instruments regarding pre-apheresis variables; however PLT yield/unit, therapeutic dose and CR showed a higher significant difference (p<0.0001) (p=0.004), being higher with Trima [7.6±1.26 (×10 11 ), 3.47±0.57 and 0.089±0.019 (platelet × 10 11 / min)]. RBC contamination was significantly higher in Haemonetics’ products (p=0.0005) in contrast to WBC contamination (p=0.1995). Conclusion: We concluded that CR and PLT yield values were more by Trima machines than Hemonetics, with no WBC contamination of both instruments’ products.