Fetal growth and hemodynamics during SARS-CoV-2 infection: a short literature review

Sechenov Medical Journal Pub Date : 2021-12-13 DOI:10.47093/2218-7332.2021.12.2.20-25

G. Rizzo, I. Mappa, P. Maqina, V. Bitsadze, J. Khizroeva, A. Makatsariya

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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that, having crossed species, has caused human disease from 2019 - COrona Virus Disease 2019 (COVID-19). Pregnant women are potentially at high risk of contracting SARS-CoV-2 infection when compared to non-pregnant matched controls. Pregnancy is also complicated with a higher risk of developing severe SARS-CoV-2, including respiratory diseases, admission to the intensive care unit and mortality, even after adjusting for confounding risk factors. Moreover, data on the effect on fetal outcome including preterm delivery and perinatal morbidity are still conflicting, the risk of vertical transmission (i.e., transmission of SARS-CoV-2 from the mother to the fetus or the newborn) is considered low but there is evidence that a significant proportion of placentas where SARS-CoV-2 occurred during pregnancy show histopathological findings suggesting placental hypoperfusion and inflammation. In this review we will present the available data on the effects of SARS-CoV-2 infection on fetal growth and maternal hemodynamics

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SARS-CoV-2感染期间胎儿生长和血流动力学:简短的文献综述

严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)是一种跨物种病毒，从2019年起导致人类疾病- 2019冠状病毒病(COVID-19)。与未怀孕的对照组相比，孕妇感染SARS-CoV-2的风险可能很高。即使在调整了混杂的风险因素后，妊娠也会伴随着发生严重SARS-CoV-2的更高风险，包括呼吸道疾病、入住重症监护病房和死亡。此外，关于对胎儿结局(包括早产和围产期发病率)的影响的数据仍然相互矛盾，垂直传播(即SARS-CoV-2从母亲传播给胎儿或新生儿)的风险被认为很低，但有证据表明，在怀孕期间发生SARS-CoV-2的胎盘中，有相当大比例的组织病理学结果显示胎盘灌注不足和炎症。在这篇综述中，我们将介绍SARS-CoV-2感染对胎儿生长和母体血液动力学影响的现有数据

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Sechenov Medical Journal

CiteScore

0.70

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0.00%

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