The role of interferon in virus infections and antibody formation.

Pathobiology annual Pub Date : 1978-01-01
G J Stanton, H M Johnson, S Baron
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Abstract

Virus-type interferon is capable of suppressing the antibody response both in vivo and in vitro. Interferon induced by antigen or mitogen (immune interferon), primarily in T-lymphocytes, also appears capable of suppressing the antibody response. Cyclic AMP has a regulatory effect on the induction of both virus-type and immune interferon. The immunosuppressive effects of virus-type and immune interferon may differ at the cellular or subcellular level.

干扰素在病毒感染和抗体形成中的作用。
病毒型干扰素在体内和体外均能抑制抗体反应。抗原或有丝分裂原诱导的干扰素(免疫干扰素),主要存在于t淋巴细胞中,似乎也能够抑制抗体反应。环状AMP对病毒型和免疫干扰素的诱导均有调节作用。病毒型和免疫干扰素的免疫抑制作用可能在细胞或亚细胞水平上有所不同。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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