Real World Data about the Characteristics of Adult Diabetes Mellitus Patients Visiting Outpatient Department of a Tertiary Care Hospital

S. Khatoon, Ghazanfer Ali, Sher Ali, Maria Zafer, Amber Ghaffar
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Abstract

Objective: To find our characteristics of adult diabetes mellitus (DM) patients visiting outpatient department (OPD) of a tertiary care hospital. Study Design: Observational, cross-sectional study. Place and Duration: Outpatient department of Medicine, Pakistan Institute of Medical Sciences, Islamabad Pakistan from October 2021 to March 2022. Methodology: We included a total of 200 patients. Inclusion criteria were patients of both genders aged 18 to 70 years having type-1 and type-2 diabetes mellitus with a disease duration history of at least 6 months visiting outpatient department. Socio-demographic data along with DM related characteristics including family history of DM, types of DM, types of medications being used and fasting/postprandial blood glucose levels were recorded. Frequency of various DM related complications at the time of enrollment were also noted. Results: In a total of 200 patients of DM, 129 (64.5%) were male and 71 (35.5%) female. Overall, mean age was 45.03±12.46 years while 91 (45.5%) patients were aged between 31 to 45 years. Mean BMI was 23.33±4.75 kg/m2. Positive family history of diabetes was found in 98 (49.0%) patients. Type-1 diabetes mellitus was reported by 13 (6.5%) patients while remaining 187 (93.5%) patients had type-2 diabetes mellitus. Mean Duration of diabetes was 7.65±7.60 years. There were 91 (45.5%) patients who were using oral plus injectable/insulin medications. Overall, mean fasting blood glucose was 148±49.06 mg/dl while mean 2-hour postprandial blood glucose was 235.07±58.80 mg/dl. Neuropathy was the most common diabetes related complications noted in 91 (45.5%) while gastrointestinal related complications were the 2nd most frequent complications observed in 31 (15.5%). Practical Implications: Vast majority of the DM patients reported hyperglycemia during routine follow ups which arises the need to revisit current management strategies. Conclusion: Majority of the patients with DM were male, middle aged and belonged to urban areas of residence. Nearly half of the DM patients reported neuropathy related complications. Keywords: Diabetes mellitus, neuropathy, hyperglycemia, insulin.
某三级医院门诊成人糖尿病患者特征的真实数据分析
目的:了解某三级医院门诊成人糖尿病(DM)患者的特点。研究设计:观察性横断面研究。地点和时间:2021年10月至2022年3月,巴基斯坦伊斯兰堡巴基斯坦医学研究所医学门诊部。方法:我们共纳入200例患者。纳入标准为年龄在18 ~ 70岁的1型和2型糖尿病患者,且病程至少6个月,就诊于门诊。记录社会人口学数据以及糖尿病相关特征,包括糖尿病家族史、糖尿病类型、正在使用的药物类型和空腹/餐后血糖水平。还记录了入组时各种糖尿病相关并发症的发生频率。结果:200例糖尿病患者中,男性129例(64.5%),女性71例(35.5%)。总体而言,平均年龄为45.03±12.46岁,91例(45.5%)患者年龄在31 ~ 45岁之间。平均BMI为23.33±4.75 kg/m2。98例(49.0%)患者有糖尿病家族史。1型糖尿病13例(6.5%),2型糖尿病187例(93.5%)。糖尿病的平均病程为7.65±7.60年。91例(45.5%)患者同时使用口服加注射/胰岛素药物。总体而言,平均空腹血糖为148±49.06 mg/dl,平均餐后2小时血糖为235.07±58.80 mg/dl。神经病变是91例患者中最常见的糖尿病相关并发症(45.5%),胃肠道相关并发症是31例患者中第二常见的并发症(15.5%)。实际意义:绝大多数糖尿病患者在常规随访中报告高血糖,这就需要重新审视当前的管理策略。结论:糖尿病患者以男性、中年、城镇居民居多。近一半的糖尿病患者报告神经病变相关并发症。关键词:糖尿病,神经病变,高血糖,胰岛素。
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