Hematological Characteristics of COVID-19 Patients Admitted to Fayoum University Hospital

Abstract

On March 11, 2020, the WHO declared the outbreak of SARS-CoV-2 a global pandemic, reporting community-scale transmissions occurring in every continent outside Antarctica. Infected patients with COVID-19 exhibit a wide spectrum of symptoms and severity; ranging from totally asymptomatic carriers to severe symptoms such as ARDS, septic shock with MOF. ARDS is the most critical clinical manifestation of COVID-19, induced mainly through immune response (i.e., cytokine storm). ACE2 is the main receptor for SARS-COV2, definitively play an important role in the pathogenesis and severity of covid-19 by its wide distribution throughout the body organs and its role in modulating the immune system. Aim of the work was to collect and analyze the hematological characteristics of patients with COVID-19 admitted at FUH. Type of the study: Retrospective cohort study. We performed a retrospective study of the hematological characteristics in confirmed cases with COVID-19 by RT-PCR hospitalized at FUH between April and July 2020. Baseline demographic data of the studied patients. The main gender was male with 69.3% percentage with mean age 37.4 ±15.6 (between 4 and 6 decade), about 61.4% of them came from rural areas. Our results revealed that, the predictor importance of CRP; it is directly related to the patient's age, positively affects the duration of hospital stay, fever and to some extent on the O2 saturation /hypoxia. Based on the current study results, we can conclude that: CRP, has perfect accuracy in predicting cases with positive RTPCR for COVID-19 and their severity. ISSN: 2536-9474 (Print) Original article / FYMJ ISSN: 2536-9482 (Online) Fayoum University Medical Journal Gomaa et al., 2022,10(1), 18-26 Page 2