Subsets of T lymphocytes and lymphocyte cooperation. Modulation of the immunocellular response.

Abstract

Recent advances in the characterization of T cell subsets suggests that the various subsets of T cells described in mice also occur in man. These various subsets of T cells can be detected by the use of appropriated antisera, co-cultivation of purified lymphoid cell preparations and differential sensitivity to radiation. Clinical applications from these new observations are now underway and it is hopeful that they should help to achieve a better understanding of the mechanisms responsible for autoimmunity, neoplasias and the various primary and secondary immunologic deficiencies.