Mitigating Breast Cancer Disparities by Addressing the Obesity Epidemic.

IF 1 Q4 ONCOLOGY

Current Breast Cancer Reports Pub Date : 2022-01-01 Epub Date: 2022-08-03 DOI:10.1007/s12609-022-00460-4

Lauren Elreda, Angelina Kim, Manmeet Malik

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引用次数: 0

Abstract

Purpose of review: Obese breast cancer patients have poorer outcomes compared to non-obese patients. The intent of this review is to discuss recent studies and analyses regarding the status of the obesity epidemic and its effect on breast cancer incidence and outcomes. Subsequently, we will introduce a program implemented at a New York City hospital to reduce the morbidity and mortality of breast cancer patients with obesity.

Recent findings: The prevalence of obesity among adult Americans is 42%, spanning all racial and socioeconomic groups. Importantly, obesity is associated with multiple chronic diseases including cancer. Among breast cancer patients, obesity is linked to higher mortality and poorer clinical outcomes, including but not limited to distant recurrence and secondary malignancies.

Summary: Current treatment of breast cancer patients does not address the link between obesity and poorer prognosis. Here, we present a general strategy for reducing the morbidity and mortality of obese breast cancer patients by addressing the obesity epidemic.

Supplementary information: The online version contains supplementary material available at 10.1007/s12609-022-00460-4.

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通过解决肥胖症流行问题减少乳腺癌差异。

审查目的：与非肥胖患者相比，肥胖乳腺癌患者的治疗效果较差。本综述旨在讨论有关肥胖症流行状况及其对乳腺癌发病率和预后影响的最新研究和分析。随后，我们将介绍纽约市一家医院为降低肥胖乳腺癌患者的发病率和死亡率而实施的一项计划：肥胖症在美国成年人中的发病率为 42%，横跨所有种族和社会经济群体。重要的是，肥胖与包括癌症在内的多种慢性疾病有关。在乳腺癌患者中，肥胖与较高的死亡率和较差的临床预后有关，包括但不限于远处复发和继发性恶性肿瘤。摘要：目前对乳腺癌患者的治疗并未解决肥胖与较差预后之间的联系。在此，我们提出了通过解决肥胖流行问题来降低肥胖乳腺癌患者发病率和死亡率的总体策略：在线版本包含补充材料，可在 10.1007/s12609-022-00460-4。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Breast Cancer Reports ONCOLOGY-

CiteScore

1.60

自引率

0.00%

发文量

期刊介绍： This journal aims to review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of breast cancer. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those with the disease. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as prevention, systemic therapy, and translational research. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.