Anti-HMGCR Myopathy without Exposure to Statins: A Case Report.

Q2 Medicine
Jorge Ferriz Vivancos, Marta Fandos Sánchez, Pilar Teresa Timoneda Timoneda, Goitzane Marcaida Benito
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引用次数: 0

Abstract

Anti-HMGCR, which was first identified in 2010, has emerged as an important mechanism of myopathogenesis in patients with exposure to statins. The availability of new detection methods has expanded the phenotypic spectrum with a subtype of population that hasn't been exposed to the drug and whose clinical, analytical, and pathological manifestations are similar. The observation by immunofluorescence of a highly specific pattern known as HALIP (HMGCR Associated Liver Immunofluorescence Pattern) can be useful in the detection of these antibodies.

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未使用他汀类药物的抗hmgcr肌病:1例报告。
抗hmgcr于2010年首次被发现,已成为他汀类药物暴露患者肌病变发生的重要机制。新检测方法的可用性扩大了未暴露于药物的人群亚型的表型谱,其临床,分析和病理表现相似。通过免疫荧光观察一种高度特异性的模式,称为HALIP (HMGCR相关肝脏免疫荧光模式),可用于检测这些抗体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.30
自引率
0.00%
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0
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