Scaling Biosafety Up During and Down After the COVID-19 Pandemic.

IF 0.5 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Applied Biosafety Pub Date : 2022-12-01 Epub Date: 2022-11-23 DOI:10.1089/apb.2022.0008

Dirk P Dittmer, Anthony B Eason, Angelica Juarez

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引用次数: 0

Abstract

Purpose: The aim of this work was to review and analyze changes to the practice of biosafety imposed by pandemics.

Methods: A narrative review of the COVID-19 pandemic that began in 2020 and prior pandemics from the perspective of a working virologist.

Results: By definition, pandemics, outbreaks, and other emergencies are transient phenomena. They manifest as waves of events that induce unforeseen needs and present unknown challenges. After a pandemic, the return to normality is as crucial as the scale-up during the exponential growth phase. The COVID-19 pandemic presents an example to study operational biosafety and biocontainment issues during community transmission of infectious agents with established pandemic potential, the propensity to induce severe disease, and the ability to disrupt aspects of human society.

Conclusions: Scaling down heightened biocontainment measures after a pandemic is as important as scaling up during a pandemic. The availability of preventive vaccines, and therapeutic drug regimens, should be considered in risk assessments for laboratory studies. There exists the need to preserve situational memory at the personal and institutional levels that can be served by professional societies.

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在COVID-19大流行期间和之后加强生物安全。

目的:这项工作的目的是审查和分析流行病给生物安全实践带来的变化。方法:从工作病毒学家的角度对2020年开始的COVID-19大流行和之前的大流行进行叙述性回顾。结果:根据定义，大流行、疫情和其他突发事件是短暂现象。它们表现为一波又一波的事件，引发不可预见的需求，并提出未知的挑战。大流行过后，恢复正常与指数增长阶段的扩大同样重要。COVID-19大流行为研究具有确定的大流行潜力、诱发严重疾病的倾向以及破坏人类社会各个方面的能力的传染病在社区传播期间的操作生物安全和生物控制问题提供了一个例子。结论:在大流行之后缩减加强的生物防护措施与在大流行期间加强同等重要。在进行实验室研究的风险评估时，应考虑到预防性疫苗和治疗性药物方案的可得性。在个人和机构层面上保存情境记忆是有必要的，这可以由专业团体来提供。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Biosafety Environmental Science-Management, Monitoring, Policy and Law

CiteScore

2.50

自引率

13.30%

发文量

期刊介绍： Applied Biosafety (APB), sponsored by ABSA International, is a peer-reviewed, scientific journal committed to promoting global biosafety awareness and best practices to prevent occupational exposures and adverse environmental impacts related to biohazardous releases. APB provides a forum for exchanging sound biosafety and biosecurity initiatives by publishing original articles, review articles, letters to the editors, commentaries, and brief reviews. APB informs scientists, safety professionals, policymakers, engineers, architects, and governmental organizations. The journal is committed to publishing on topics significant in well-resourced countries as well as information relevant to underserved regions, engaging and cultivating the development of biosafety professionals globally.