{"title":"Post-treatment course of acute lipodermatosclerosis.","authors":"Kotaro Suehiro, Noriyasu Morikage, Takasuke Harada, Yuriko Takeuchi, Takahiro Mizoguchi, Soichi Ike, Ryo Otuska, Hiroshi Kurazumi, Ryo Suzuki, Kimikazu Hamano","doi":"10.1177/02683555221147473","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to clarify whether acute lipodermatosclerosis (LDS) progress to chronic LDS without continued compression therapy.</p><p><strong>Methods: </strong>Between April 2015 and November 2021, 30 patients with acute/subacute LDS, which was diagnosed clinically by presence of isolated, poorly demarcated, tender erythema, and induration limited to the lower leg(s), visited our clinic and were able to be followed up for longer than a year. We reviewed their treatment results and the post-treatment courses.</p><p><strong>Results: </strong>In all cases, the symptoms in the acute phase subsided with compression bandages. After the discontinuation of compression therapy, 18 legs (56%) progressed to chronic LDS, and 14 legs (44%) did not. In the legs without progression, subcutaneous tissue in the affected leg was thicker compared with that in the contralateral leg (median 19.1 mm vs. 13.4 mm, <i>p</i> < 0.05) on the initial visit. In the legs with progression, the difference in subcutaneous tissue thickness between the affected and unaffected legs was not significant (10.0 mm vs. 7.6 mm).</p><p><strong>Conclusions: </strong>Our findings suggest that in legs which later progress to chronic LDS, subcutaneous tissue contraction due to panniculitis is already present during the acute phase; therefore, long-term compression therapy is unlikely to improve the prognosis.</p>","PeriodicalId":20139,"journal":{"name":"Phlebology","volume":"38 2","pages":"73-79"},"PeriodicalIF":1.6000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phlebology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/02683555221147473","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 1
Abstract
Objectives: We aimed to clarify whether acute lipodermatosclerosis (LDS) progress to chronic LDS without continued compression therapy.
Methods: Between April 2015 and November 2021, 30 patients with acute/subacute LDS, which was diagnosed clinically by presence of isolated, poorly demarcated, tender erythema, and induration limited to the lower leg(s), visited our clinic and were able to be followed up for longer than a year. We reviewed their treatment results and the post-treatment courses.
Results: In all cases, the symptoms in the acute phase subsided with compression bandages. After the discontinuation of compression therapy, 18 legs (56%) progressed to chronic LDS, and 14 legs (44%) did not. In the legs without progression, subcutaneous tissue in the affected leg was thicker compared with that in the contralateral leg (median 19.1 mm vs. 13.4 mm, p < 0.05) on the initial visit. In the legs with progression, the difference in subcutaneous tissue thickness between the affected and unaffected legs was not significant (10.0 mm vs. 7.6 mm).
Conclusions: Our findings suggest that in legs which later progress to chronic LDS, subcutaneous tissue contraction due to panniculitis is already present during the acute phase; therefore, long-term compression therapy is unlikely to improve the prognosis.
目的:我们的目的是澄清急性脂质皮肤硬化(LDS)是否在没有持续压迫治疗的情况下进展为慢性LDS。方法:2015年4月至2021年11月,30例急性/亚急性LDS患者来我院就诊,临床诊断为孤立性、界限不清、鲜嫩红斑和仅限于小腿的硬结。我们回顾了他们的治疗结果和治疗后的过程。结果:所有病例的急性期症状均通过压迫绷带缓解。停止压迫治疗后,18条腿(56%)进展为慢性LDS, 14条腿(44%)没有进展。在没有进展的腿中,首次就诊时受影响腿的皮下组织比对侧腿厚(中位数19.1 mm比13.4 mm, p < 0.05)。在进展的腿中,受影响的腿和未受影响的腿之间的皮下组织厚度差异不显著(10.0 mm vs. 7.6 mm)。结论:我们的研究结果表明,在后来进展为慢性LDS的腿部,由于全身炎引起的皮下组织收缩在急性期已经存在;因此,长期压迫治疗不太可能改善预后。
期刊介绍:
The leading scientific journal devoted entirely to venous disease, Phlebology is the official journal of several international societies devoted to the subject. It publishes the results of high quality studies and reviews on any factor that may influence the outcome of patients with venous disease. This journal provides authoritative information about all aspects of diseases of the veins including up to the minute reviews, original articles, and short reports on the latest treatment procedures and patient outcomes to help medical practitioners, allied health professionals and scientists stay up-to-date on developments.
Print ISSN: 0268-3555