Transcatheter edge-to-edge mitral valve repair in mitral regurgitation: current status and future prospects.

IF 2.9 3区医学 Q3 ENGINEERING, BIOMEDICAL

Expert Review of Medical Devices Pub Date : 2023-02-01 DOI:10.1080/17434440.2022.2098013

Lukas Stolz, Daniel Braun, Satoshi Higuchi, Martin Orban, Philipp M Doldi, Thomas J Stocker, Ludwig T Weckbach, Mirjam G Wild, Christian Hagl, Steffen Massberg, Michael Näbauer, Jörg Hausleiter, Mathias Orban

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引用次数: 4

Abstract

ABSTRACT Introduction Mitral regurgitation (MR) is associated with substantial morbidity and mortality. Within the past 15 years, mitral valve edge-to-edge repair (M-TEER) has developed from an experimental approach to a guideline-recommended, safe, and effective treatment option for patients with severe primary or secondary mitral regurgitation. Areas covered This review covered relevant publications of M-TEER and summarizes the development of M-TEER devices within the last 15 years. It outlines anatomical challenges which drove the evolution of M-TEER devices, provides an overview about the current state of clinical application and research, and offers an outlook into the future of transcatheter mitral valve treatment. Expert opinion The development and refinement of new M-TEER device generations offer the possibility to treat a wide range of mitral valve anatomies. Choosing the best device for the individual anatomic properties of the patients and considering comorbidities is the key to maximized MR reduction, minimalized complication rates, and thus optimized postinterventional prognosis. Independent from prognostic implications, quality of life has become an important patient-centered outcome that can be improved by M-TEER in virtually all patients treated.

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经导管二尖瓣边缘到边缘修复二尖瓣反流:现状及未来展望。

二尖瓣反流(MR)与大量的发病率和死亡率相关。在过去的15年里，二尖瓣边缘到边缘修复(M-TEER)已经从一种实验方法发展成为一种指南推荐的、安全有效的治疗方案，用于严重的原发性或继发性二尖瓣反流患者。涵盖领域:本综述涵盖了M-TEER的相关出版物，并总结了近15年来M-TEER设备的发展。它概述了驱动M-TEER装置发展的解剖学挑战，概述了目前的临床应用和研究状况，并展望了经导管二尖瓣治疗的未来。专家意见:新一代M-TEER装置的发展和改进为治疗广泛的二尖瓣解剖提供了可能性。根据患者的个体解剖特性选择最佳的器械并考虑合并症是最大限度地降低MR，减少并发症发生率，从而优化介入后预后的关键。与预后无关，生活质量已成为一个重要的以患者为中心的结果，几乎所有接受M-TEER治疗的患者都可以通过M-TEER改善生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Medical Devices 医学-工程：生物医学

CiteScore

5.90

自引率

3.20%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal serves the device research community by providing a comprehensive body of high-quality information from leading experts, all subject to rigorous peer review. The Expert Review format is specially structured to optimize the value of the information to reader. Comprehensive coverage by each author in a key area of research or clinical practice is augmented by the following sections: Expert commentary - a personal view on the most effective or promising strategies Five-year view - a clear perspective of future prospects within a realistic timescale Key issues - an executive summary cutting to the author''s most critical points In addition to the Review program, each issue also features Medical Device Profiles - objective assessments of specific devices in development or clinical use to help inform clinical practice. There are also Perspectives - overviews highlighting areas of current debate and controversy, together with reports from the conference scene and invited Editorials.