The Direction of Flow and Phase-encoding Schemes Effects on Signal Intensity in T1-weighted Inversion Recovery TurboFLASH Images.

Q3 Medicine

Journal of Biomedical Physics and Engineering Pub Date : 2023-02-01 DOI:10.31661/jbpe.v0i0.2203-1468

Mahmood Nazarpoor

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引用次数: 0

Abstract

Background: It is needed to minimize the effect of flow direction on the desired area, such as arterial input function (AIF) in magnetic resonance imaging (MRI).

Objective: The current study aimed to investigate the effect of flow direction on different velocities (0-80.39 cm/s) for the strength of the signal intensity (SI) at the linear phase-encoding (LPE) and the center out phase-encoding (COPE) schemes and to recommend the best flow direction in a selected slice and scheme for absolute perfusion measurement by inversion recovery T1-weighted turbo fast low-angle shot (TurboFLASH) MR images.

Material and methods: In this experimental study, the flow rates were measured using a flow phantom, and the signal intensity (SI) was measured at the two opposite flow directions in the Z-axis perpendicular to the coronal image at a concentration of 0.8 mmol/L of gadolinium-diethylenetriaminepantaacetic acid (Gd-DTPA) by using the LPE and COPE schemes.

Results: The increase in velocity along with the growth in SI and inflow affected the use of LPE and COPE acquisitions in both directions. The velocity of the arterial input function is needed to calculate the inflow correction factor by using two schemes in two opposite flow directions to investigate perfusion.

Conclusion: The COPE scheme was better than the LPE scheme in measuring perfusion since the velocity and direction of blood flow affect SI less.

Abstract Image

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流方向和相位编码对t1加权反演恢复图像信号强度的影响。

背景:需要将血流方向对所需区域的影响最小化，例如磁共振成像(MRI)中的动脉输入功能(AIF)。目的:本研究旨在探讨不同流速(0-80.39 cm/s)下线性相位编码(LPE)和中心向外相位编码(COPE)方案下信号强度(SI)的方向影响，并为t1加权turbo快速低角度拍摄(TurboFLASH) MR图像反演恢复推荐最佳的流方向和绝对灌注测量方案。材料与方法:在本实验研究中，采用流动模体测量流速，并采用LPE和COPE方案，在浓度为0.8 mmol/L的钆-二乙烯三胺乙酸(Gd-DTPA)浓度下，在垂直于冠状像的z轴上测量两个相反流动方向上的信号强度(SI)。结果:随着SI和流入的增加，流速的增加在两个方向上影响了LPE和COPE的使用。采用两种方案在两个相反的流动方向上研究灌注情况，需要动脉输入函数的速度来计算流入校正因子。结论:COPE方案比LPE方案更适合于测量血流灌注，血流速度和方向对SI的影响较小。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Biomedical Physics and Engineering Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： The Journal of Biomedical Physics and Engineering (JBPE) is a bimonthly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research (experimental or theoretical) broadly concerned with the relationship of physics to medicine and engineering.