Extragonadal germ cell tumor: A rare case in dorsal region.

IF 0.9 4区 医学 Q4 ONCOLOGY
Indian journal of cancer Pub Date : 2024-01-01 Epub Date: 2023-01-10 DOI:10.4103/ijc.ijc_880_21
Maria Teresa Paparella, Laura Eusebi, Gaia Goteri, Francesco Bartelli, Giuseppe Guglielmi
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引用次数: 0

Abstract

Abstract: Extragonadal germ cell tumors (GCTs) are a rare group of neoplasms that account for 1%-5% of all GCTs. These tumors can present with an unpredictable behavior and clinical manifestations depending on different factors such as histological subtype, anatomical site, and clinical stage. We report the case of a 43-year-old male patient with a primitive extragonadal seminoma located in the paravertebral dorsal region, an extremely rare site. He presented to our emergency department with a 3-month history of back pain and a 1-week history of fever of unknown origin. Imaging techniques revealed a solid tissue arising from the vertebral bodies of D9-D11 and extending in the paravertebral space. After a bone marrow biopsy and exclusion of testicular seminoma, he was diagnosed with primitive extragonadal seminoma. The patient underwent five cycles of chemotherapy, and the follow-up CT examinations showed a reduction of the mass initially till a complete remission with no evidence of recurrence.

生殖细胞瘤:背区罕见病例。
绒毛膜外生殖细胞瘤(GCT)是一类罕见的肿瘤,占所有 GCT 的 1%-5%。根据组织学亚型、解剖部位和临床分期等不同因素,这些肿瘤的表现和临床表现难以预测。我们报告了一例 43 岁男性患者的病例,他患有位于椎旁背侧的原始对角外精原细胞瘤,这是一个极其罕见的部位。患者因背部疼痛 3 个月和不明原因发热 1 周来我院急诊科就诊。影像学检查发现,D9-D11椎体上长出一个实体组织,并延伸至椎旁间隙。经过骨髓活检并排除睾丸精原细胞瘤后,他被诊断为原始对角外精原细胞瘤。患者接受了五个周期的化疗,随访的 CT 检查显示,肿块从最初的缩小到完全缓解,且无复发迹象。
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来源期刊
Indian journal of cancer
Indian journal of cancer Medicine-Oncology
CiteScore
1.40
自引率
0.00%
发文量
67
审稿时长
>12 weeks
期刊介绍: Indian Journal of Cancer (ISSN 0019-509X), the show window of the progress of ontological sciences in India, was established in 1963. Indian Journal of Cancer is the first and only periodical serving the needs of all the specialties of oncology in India.
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