Outcomes of ureteroscopy for management of stone disease in early and late childhood over a 15-year period.

IF 2.6 4区 医学 Q2 UROLOGY & NEPHROLOGY
Mriganka Sinha, Amelia Pietropaolo, Yesica Quiroz Madarriaga, Erika Llorens de Knecht, Anna Bujons Tur, Stephen Griffin, Bhaskar K Somani
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引用次数: 0

Abstract

Background: Although paediatric ureteroscopy is widely performed, there is still a lack of data and outcomes in early childhood. In this two-centre study, we compared the outcomes of ureteroscopy for stone disease management in early and late childhood and provide outcomes for the same.

Methods: Data was retrospectively collected on consecutive patients from two tertiary paediatric endo-urology European centres over a 15-year period (2006-2021). Patients were split into two groups, namely, early childhood (age ⩽ 9 years) and late childhood (age 9 to ⩽16 years). Outcomes including stone-free rate (SFR) and complications were compared between these two groups.

Results: A total of 148 patients underwent 184 procedures (1.2 procedure/patient) during the study period (66 in early childhood and 82 in late childhood). The mean age in early and late childhood groups were 5.6 and 13.3 years, and a male: female ratio of 1.6:1 and 1.1:1, respectively. The SFR and complications in early and late childhood groups were 87.8% and 90.2% (p = 0.64) and 5.7% and 4.1%, respectively.

Conclusion: Paediatric ureteroscopy and laser stone fragmentation achieves good results in both early and late childhood with comparable SFRs, although the complications and need for second procedure were marginally higher in the early childhood group. Our study would set up a new benchmark for patient counselling in future, and perhaps this needs to be reflected in the paediatric urolithiasis guidelines.

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15年期间输尿管镜治疗儿童早期和晚期结石疾病的结果
背景:虽然儿科输尿管镜检查被广泛应用,但在儿童早期仍然缺乏数据和结果。在这项双中心研究中,我们比较了输尿管镜治疗儿童早期和晚期结石疾病的结果,并提供了相同的结果。方法:回顾性收集来自欧洲两所三级儿科泌尿外科中心15年(2006-2021年)的连续患者的数据。患者分为两组,即儿童早期(年龄≥9岁)和儿童晚期(年龄≥9 ~ 16岁)。比较两组患者的无结石率(SFR)和并发症。结果:在研究期间,共有148名患者接受了184次手术(1.2次/患者)(66例儿童早期,82例儿童晚期)。儿童早期组和儿童晚期组的平均年龄分别为5.6岁和13.3岁,男女比例分别为1.6:1和1.1:1。儿童期早期和晚期组SFR和并发症发生率分别为87.8%和90.2% (p = 0.64)和5.7%和4.1%。结论:儿童输尿管镜和激光结石碎裂术在儿童期早期和晚期均取得了良好的效果,但早期组的并发症和第二次手术的需求略高。我们的研究将为未来的患者咨询建立一个新的基准,也许这需要在儿科尿石症指南中得到反映。
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
39
审稿时长
10 weeks
期刊介绍: Therapeutic Advances in Urology delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of urology. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers in urology, providing a forum in print and online for publishing the highest quality articles in this area. The editors welcome articles of current interest across all areas of urology, including treatment of urological disorders, with a focus on emerging pharmacological therapies.
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