Effects of ambient particulate matter on vascular tissue: a review.

IF 6.4 2区医学 Q1 ENVIRONMENTAL SCIENCES

Journal of Toxicology and Environmental Health-Part B-Critical Reviews Pub Date : 2020-10-02 DOI:10.1080/10937404.2020.1822971

Kristina Shkirkova, Krista Lamorie-Foote, Michelle Connor, Arati Patel, Giuseppe Barisano, Hans Baertsch, Qinghai Liu, Todd E Morgan, Constantinos Sioutas, William J Mack

引用次数: 42

Abstract

Fine and ultra-fine particulate matter (PM) are major constituents of urban air pollution and recognized risk factors for cardiovascular diseases. This review examined the effects of PM exposure on vascular tissue. Specific mechanisms by which PM affects the vasculature include inflammation, oxidative stress, actions on vascular tone and vasomotor responses, as well as atherosclerotic plaque formation. Further, there appears to be a greater PM exposure effect on susceptible individuals with pre-existing cardiovascular conditions.

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环境颗粒物对血管组织的影响

细颗粒物和超细颗粒物(PM)是城市空气污染的主要成分，也是公认的心血管疾病危险因素。本综述研究了PM暴露对血管组织的影响。PM影响血管系统的具体机制包括炎症、氧化应激、对血管张力和血管舒缩反应的作用，以及动脉粥样硬化斑块的形成。此外，对于已有心血管疾病的易感个体，PM暴露的影响似乎更大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Toxicology and Environmental Health-Part B-Critical Reviews 环境科学-毒理学

CiteScore

13.80

自引率

6.90%

发文量

审稿时长

>24 weeks

期刊介绍： "Journal of Toxicology and Environmental Health: Part B - Critical Reviews" is an academic journal published by Taylor & Francis, focusing on the critical examination of research in the areas of environmental exposure and population health. With an ISSN identifier of 1093-7404, this journal has established itself as a significant source of scholarly content in the field of toxicology and environmental health. Since its inception, the journal has published over 424 articles that have garnered 35,097 citations, reflecting its impact and relevance in the scientific community. Known for its comprehensive reviews, the journal also goes by the names "Critical Reviews" and "Journal of Toxicology & Environmental Health, Part B, Critical Reviews." The journal's mission is to provide a platform for in-depth analysis and critical discussion of the latest findings in toxicology, environmental health, and related disciplines. By doing so, it contributes to the advancement of knowledge and understanding of the complex interactions between environmental factors and human health, aiding in the development of strategies to protect and improve public health.