Axillary Lymph Node Uptake on ¹⁸F-FDG PET/CT after COVID-19 Vaccination: A Direct Comparison Study with Influenza Vaccination.

IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Molecular Imaging and Radionuclide Therapy Pub Date : 2023-02-23 DOI:10.4274/mirt.galenos.2022.27136

Yoichi Otomi, Takayoshi Shinya, Hiroto Kasai, Naoko Okada, Tomoki Matsushita, Kohei Higashi, Saya Matsuzaki, Yuka Hiroshima, Michiko Kubo, Hideki Otsuka, Masafumi Harada

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引用次数: 1

Abstract

Objectives: To compare vaccinated-side axillary lymph node uptake on ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) after coronavirus disease-2019 (COVID-19) and influenza vaccination.

Methods: We retrospectively analyzed 177 patients who underwent ¹⁸F-FDG PET/CT after COVID-19 or influenza vaccination. We compared the uptake of the vaccinated-side axillary lymph nodes of 109 COVID-19 vaccinated patients with those of a lot of influenza-vaccinated patients. We also compared the uptake between 66 patients who received the first COVID-19 vaccination with 43 who received the second COVID-19 vaccination.

Results: ¹⁸F-FDG-avid axillary lymph nodes on the vaccinated side were significantly more frequently observed in the COVID-19 group (45%) than in the influenza group (19%) (p<0.001). When the interval between vaccination to PET/CT was within 7 days, there was no significant difference in the frequency of ¹⁸F-FDG-avid vaccinated-side axillary lymph nodes between the groups (COVID-19 group: 41% vs. influenza group: 45%, p=0.724). When the interval was over 7 days, ¹⁸F-FDG-avid lymph nodes were much more frequent in the COVID-19 group (47%) than in the influenza group (7%) (p<0.001). Comparing the first and second COVID-19 groups, ¹⁸F-FDG-avid lymph nodes were more frequent in the second vaccination group than in the first vaccination group, but the difference was not significant.

Conclusion: ¹⁸F-FDG-avid vaccinated-side axillary lymph nodes were more frequently observed in the COVID-19 group than in the influenza group. In the case of the COVID-19 vaccine, a delay of ¹⁸F-FDG PET/CT examination is recommended by a longer interval from vaccination than in the influenza vaccine.

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COVID-19疫苗接种后腋窝淋巴结18F-FDG PET/CT摄取:与流感疫苗接种的直接比较研究

目的:比较2019冠状病毒病(COVID-19)和流感疫苗接种后接种侧腋窝淋巴结在18f -氟脱氧葡萄糖(FDG)正电子发射断层扫描/计算机断层扫描(PET/CT)上的摄取情况。方法:回顾性分析177例在COVID-19或流感疫苗接种后接受18F-FDG PET/CT检查的患者。我们比较了109例COVID-19疫苗接种患者与大量流感疫苗接种患者接种侧腋窝淋巴结的摄取情况。我们还比较了66名首次接种COVID-19疫苗的患者与43名第二次接种COVID-19疫苗的患者之间的摄取情况。结果:新冠肺炎组免疫侧18F-FDG-avid腋窝淋巴结发生率(45%)明显高于流感组(19%)(两组间p18F-FDG-avid接种侧腋窝淋巴结发生率(41% vs.流感组:45%，p=0.724)。当间隔超过7 d时，COVID-19组的18F-FDG-avid淋巴结发生率(47%)远高于流感组(7%)，而第二次接种组的p18F-FDG-avid淋巴结发生率高于第一次接种组，但差异不显著。结论:新冠肺炎组18f - fdg免疫侧腋窝淋巴结发生率高于流感组。对于COVID-19疫苗，建议延迟接种18F-FDG PET/CT检查，间隔时间比流感疫苗更长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.