Intravesical bacillus Calmette-Guérin-induced myopathy presenting as rhabdomyolysis: a case report.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Journal of Yeungnam medical science Pub Date : 2023-10-01 Epub Date: 2023-02-13 DOI:10.12701/jyms.2022.00850
Chae Hun Lee, Byeong Joo Choi, Jung Hun Kim, Tae Woong Yang, Gi Jeong Kim, Ha Young Shin, Se Hoon Kim, Seung Woo Kim
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引用次数: 0

Abstract

Intravesical bacillus Calmette-Guérin (BCG) instillation is an adjuvant treatment for non-muscle-invasive urinary bladder cancer. Although most complications associated with BCG immunotherapy are mild and self-limiting, rare albeit serious complications have been reported. Only a few cases of BCG-related rhabdomyolysis have been reported. In this study, we present the case of a 72-year-old woman who developed severe weakness and hyperCKemia following intravesical BCG instillation. A muscle biopsy was performed, and a diagnosis of drug-induced myopathy was made.

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膀胱内注射Calmette Guérin杆菌引起的以横纹肌溶解症表现的肌病:一例报告。
膀胱内滴注卡氏杆菌(BCG)是非肌肉浸润性膀胱癌症的辅助治疗方法。尽管大多数与BCG免疫疗法相关的并发症都是轻度和自限性的,但也有罕见但严重的并发症报道。只有少数与BCG相关的横纹肌溶解症病例被报道。在这项研究中,我们介绍了一例72岁的女性,她在膀胱内滴注BCG后出现严重虚弱和高CK血症。进行了肌肉活检,诊断为药物性肌病。
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