Lessons Learned from the ISCHEMIA Trial for the Management of Patients with Stable Ischemic Heart Disease.

IF 15.1 1区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
William E Boden, Peter H Stone
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引用次数: 0

Abstract

The recent landmark International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial was undertaken to assess whether stable angina patients with moderate to severe baseline ischemia would benefit from an invasive approach with revascularization versus a conservative approach of intensive lifestyle intervention and pharmacologic secondary prevention. This trial addressed the hypothesis that treating ischemia with an invasive approach would reduce major adverse cardiac events more than a noninvasive pharmacologic and lifestyle approach. ISCHEMIA is discussed in detail, along with current implications for contemporary management of this very common cardiac disorder afflicting millions of patients worldwide.

稳定性缺血性心脏病患者缺血试验的经验教训
最近一项具有里程碑意义的医学和侵入性方法(ISCHEMIA)比较健康效果的国际研究进行了研究,以评估中度至重度基线缺血的稳定型心绞痛患者是否可以从侵入性方法和血运重建术中获益,而不是采用强化生活方式干预和药物二级预防的保守方法。该试验提出了一个假设,即采用有创方法治疗缺血比采用无创药物和生活方式治疗更能减少主要的心脏不良事件。详细讨论了缺血,以及当前对这种非常常见的心脏疾病的当代管理的影响,这种疾病折磨着全世界数百万患者。
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来源期刊
Annual review of medicine
Annual review of medicine 医学-医学:内科
CiteScore
24.90
自引率
0.00%
发文量
58
期刊介绍: The Annual Review of Medicine, which has been published since 1950, focuses on important advancements in diverse areas of medicine. These include AIDS/HIV, cardiology, clinical pharmacology, dermatology, endocrinology/metabolism, gastroenterology, genetics, immunology, infectious disease, neurology, oncology/hematology, pediatrics, psychiatry, pulmonology, reproductive medicine, and surgery. The journal's current volume has transitioned from a gated access model to an open access model through the Annual Reviews' Subscribe to Open program. All articles published in the journal are now available under a CC BY license.
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