Use of equine chorionic gonadotropin in lactating dairy cattle: a rapid review.

IF 1.1 4区农林科学 Q3 VETERINARY SCIENCES

New Zealand veterinary journal Pub Date : 2023-03-01 DOI:10.1080/00480169.2022.2139306

L H Beasley, N Cogger, Cwr Compton

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引用次数: 0

Abstract

Aims: To use an evidence-based approach to evaluate the available research data on the efficacy of equine chorionic gonadotropin (eCG) to improve reproductive performance of dairy cows when added to oestrus synchronisation programmes for the treatment of cows not detected in oestrus.

Methods: A rapid literature review was conducted to summarise the existing trial data, primarily the effect of eCG on conception rate (CR) to fixed time artificial insemination (FTAI) from oestrus synchronisation programmes in lactating dairy cows. Relevant papers were identified via databases and auxiliary search strategies, then information was collected using a standardised data collection form. Similar studies were grouped together to create a descriptive summary of CR to FTAI and secondary outcome measures, with the creation of forest plots to visualise results.

Results: A total of 15 studies were identified for review: nine examined the administration of 400-500 IU eCG as part of an oestrus synchronisation programme based on intra-vaginal progesterone-releasing devices, gonadotropin-releasing hormone and prostaglandin (P4-GPG programme). The variable methodologies in the trials evaluated posed difficulties in grouping studies for further analysis and meant that there was insufficient data for a full meta-analysis. A single study reported a statistically significant increase in CR to FTAI from the addition to eCG to a P4-GPG programme in cows with anovulatory anoestrous. Four studies evaluated the addition of eCG to P4-GPG programmes in cows without visible oestrous signs; risk differences for CR to FTAI were between -1.7% and 28.8%, with three out of four studies reporting a positive effect of eCG on CR to FTAI, but all 95% CI values crossed the line of no effect. Two studies reported on the effect of eCG on 42-day pregnancy rate following a P4-GPG programme; one reported a risk difference of -4.9% (95% CI = -10.6-0.8%), while the other reported a risk difference of 7.9% (95% CI = 0.8-15%).

Conclusions: The results of published studies describing the effect of eCG in P4-GPG programmes on CR to FTAI are inconsistent and further well-designed, adequately powered studies with standardised outcome measures are required to investigate its effect.

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马绒毛膜促性腺激素在泌乳奶牛中的应用综述。

目的:利用基于证据的方法，评估现有的研究数据，即将马绒毛膜促性腺激素(eCG)添加到发情同步计划中，用于治疗未检测到发情的奶牛，以提高奶牛的繁殖性能。方法:快速回顾文献，总结现有试验数据，主要是eCG对发情同步程序中泌乳期奶牛受孕率(CR)和固定时间人工授精(FTAI)的影响。通过数据库和辅助搜索策略识别相关论文，然后使用标准化数据收集表收集信息。将类似的研究分组在一起，以创建CR到FTAI和次要结果测量的描述性摘要，并创建森林图以可视化结果。结果:总共有15项研究被确定用于审查:9项研究检查了400-500 IU eCG作为基于阴道内黄体酮释放装置，促性腺激素释放激素和前列腺素(P4-GPG计划)的发情同步计划的一部分。试验评估中的可变方法给进一步分析分组研究带来了困难，这意味着没有足够的数据进行完整的荟萃分析。一项单独的研究报告了在无排卵不发情的奶牛中，从eCG到P4-GPG程序的CR到FTAI的统计学显著增加。四项研究评估了在没有明显发情迹象的奶牛中添加eCG和P4-GPG程序;CR至FTAI的风险差异在-1.7%至28.8%之间，四分之三的研究报告了eCG对CR至FTAI的积极影响，但所有95% CI值都越过了无影响的界限。两项研究报道了P4-GPG方案后心电图对42天妊娠率的影响;其中一个报告的风险差异为-4.9% (95% CI = -10.6-0.8%)，而另一个报告的风险差异为7.9% (95% CI = 0.8-15%)。结论:已发表的研究描述P4-GPG方案中eCG对CR至FTAI的影响的结果不一致，需要进一步设计良好，具有标准化结果测量的充分有力的研究来调查其影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

New Zealand veterinary journal 农林科学-兽医学

CiteScore

3.00

自引率

0.00%

发文量

审稿时长

12-24 weeks

期刊介绍： The New Zealand Veterinary Journal (NZVJ) is an international journal publishing high quality peer-reviewed articles covering all aspects of veterinary science, including clinical practice, animal welfare and animal health. The NZVJ publishes original research findings, clinical communications (including novel case reports and case series), rapid communications, correspondence and review articles, originating from New Zealand and internationally. Topics should be relevant to, but not limited to, New Zealand veterinary and animal science communities, and include the disciplines of infectious disease, medicine, surgery and the health, management and welfare of production and companion animals, horses and New Zealand wildlife. All submissions are expected to meet the highest ethical and welfare standards, as detailed in the Journal’s instructions for authors.