Comparison of Parameters of Fetal Doppler Echocardiography Between Mothers with and Without Diabetes.

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM
Parichehr Pooransari, Sahar Mehrabi, Masoumeh Mirzamoradi, Soraya Salehgargari, Maryam Afrakhteh
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引用次数: 0

Abstract

Background: The current study aimed to compare fetal myocardial function and ventricular thickness in diabetic and normal pregnancies.

Methods: Women with singleton pregnancies in the second or third trimester who were referred for routine prenatal or anomaly ultrasounds within March 2020 to February 2021 were enrolled in the study. Women with a positive history of overt or gestational diabetes mellitus (GDM) were considered the case group (n = 50), and women without GDM were considered the control group (n = 50). The study did not include women with multifetal pregnancy, hypertension, intrauterine growth retardation, and polyhydramnios. A complete fetal Doppler echocardiography was performed to measure isovolumic relaxation time (IVRT), left myocardial performance index (MPI), E/A ratio, right and left ventricular wall thickness, and end-diastolic interventricular septal thickness (IVST). The data were analyzed using three types of decision tree (DT) algorithms, and the performance of each DT was measured on the testing dataset.

Results: The frequency of IVRT > 41 milliseconds was significantly higher in the case group than in the control group. The mean MPI values were 0.53 ± 0.15 and 0.43 ± 0.09 (P < 0.05), respectively, and the mean IVST values were 3.3 ± 1.11 and 2.49 ± 0.55 mm (P < 0.05) in the case and control groups, respectively, but not different between the subjects with overt or GDM (P > 0.05). Additionally, in the case group, the mean left MPI values were 0.57 ± 0.18 and 0.49 ± 0.12 in participants with poor and good glycemic control, respectively (P = 0.12).

Conclusions: Complete prenatal echocardiography performed in the second or third trimester is an appropriate tool for the diagnosis of fetal cardiac dysfunction in diabetic mothers and is suggested to perform for diabetic mothers, even those with good glycemic control.

Abstract Image

Abstract Image

糖尿病母亲与非糖尿病母亲胎儿多普勒超声心动图参数比较。
背景:本研究旨在比较糖尿病和正常妊娠的胎儿心肌功能和心室厚度。方法:在2020年3月至2021年2月期间进行常规产前或异常超声检查的妊娠中期或晚期单胎妊娠妇女纳入研究。有明显或妊娠期糖尿病(GDM)病史的妇女被认为是病例组(n = 50),没有GDM的妇女被认为是对照组(n = 50)。该研究没有包括多胎妊娠、高血压、宫内生长迟缓和羊水过多的妇女。采用全胎多普勒超声心动图测量等容舒张时间(IVRT)、左心肌表现指数(MPI)、E/A比、左右心室壁厚度、舒张末期室间隔厚度(IVST)。使用三种类型的决策树(DT)算法对数据进行分析,并在测试数据集上测量每种DT算法的性能。结果:病例组IVRT > 41毫秒的频率明显高于对照组。病例组和对照组的MPI平均值分别为0.53±0.15和0.43±0.09 (P < 0.05), IVST平均值分别为3.3±1.11和2.49±0.55 mm (P < 0.05),显性和GDM组之间差异无统计学意义(P > 0.05)。此外,在病例组中,血糖控制较差和良好的参与者的平均左MPI值分别为0.57±0.18和0.49±0.12 (P = 0.12)。结论:在妊娠中期或晚期进行完整的产前超声心动图是诊断糖尿病母亲胎儿心功能障碍的合适工具,建议对糖尿病母亲进行超声心动图检查,即使是血糖控制良好的孕妇。
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来源期刊
CiteScore
3.10
自引率
4.80%
发文量
0
期刊介绍: The aim of the International Journal of Endocrinology and Metabolism (IJEM) is to increase knowledge, stimulate research in the field of endocrinology, and promote better management of patients with endocrinological disorders. To achieve this goal, the journal publishes original research papers on human, animal and cell culture studies relevant to endocrinology.
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