Successful treatment of multidrug-resistant Pseudomonas aeruginosa keratitis with meropenem eye drops - a case report.

IF 2.9 Q1 OPHTHALMOLOGY
Carolin Elhardt, Armin Wolf, Christian Maximilian Wertheimer
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引用次数: 0

Abstract

Background: This case report describes the course and therapeutic management of a fast-spreading bacterial keratitis caused by multidrug-resistant (MDR) Pseudomonas aeruginosa (P. aeruginosa).

Case presentation: A 27-year-old male contact lens wearer presented with a multi-resistant, fast spreading P. aeruginosa keratitis. After initial resistance to various antibiotic therapies, testing revealed a MDR P. aeruginosa. The keratitis was treated successfully with specially prepared 50 mg/ml off-label meropenem eye drops for 18 days as well as systemic meropenem for seven days with rapid improvement of the corneal infiltrate.

Conclusion: This case report demonstrates the combination of topical and systemic meropenem as a useful treatment option for corneal ulcers caused by MDR P. aeruginosa.

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美罗培南滴眼液成功治疗耐多药铜绿假单胞菌角膜炎1例报告。
背景:本病例报告描述了由多重耐药(MDR)铜绿假单胞菌(P. aeruginosa)引起的快速传播的细菌性角膜炎的病程和治疗管理。病例介绍:一名27岁男性隐形眼镜佩戴者患有多重耐药、快速传播的铜绿假单胞菌性角膜炎。在最初对各种抗生素治疗产生耐药性后,检测发现了耐多药铜绿假单胞菌。经特殊配制的超说明书美罗培南滴眼液50 mg/ml治疗18天,并用全身美罗培南治疗7天,角膜浸润迅速改善。结论:本病例报告表明,局部和全身联合使用美罗培南是耐多药铜绿假单胞菌引起的角膜溃疡的有效治疗选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.80
自引率
3.40%
发文量
39
审稿时长
13 weeks
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