Comparison of blood gas results obtained on Abbott i-Stat® and on Radiometer ABL 800 Flex® analyzers Impact for the clinical decision

IF 0.4 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Annales de biologie clinique Pub Date : 2022-11-01 DOI:10.1684/abc.2022.1765

Romain Jouffroy, Maude Laney, Teddy Leguillier, Valérie Nivet-Antoine, Jean-Louis Beaudeux

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引用次数: 0

Abstract

Background: Point of care testing (POCT) tests are needed to assess severity and to help for triage in hospital and in prehospital settings. Before their use, the analytical performances of POCTs have to be compared with central laboratory reference methods. In this study, we describe the comparability of results obtained by either the Abbott i-STAT® System POCT handheld device or the blood gases analyzer of the central laboratory of our hospital.

Methods: Sample blood from 37 septic patients admitted to the intensive care unit (ICU) were assayed by Abbott i-STAT® System POCT and Radiometer ABL800 Flex® lab analyzer. Studied parameters were as follows: pH, pO2, pCO2, base excess (BE), HCO3- and lactate. Comparability was evaluated using Bland-Altman method. The clinical value for possible mismatch issued of values differences was also assessed.

Results: Quite acceptable correlations in results of POCT and laboratory analyzer were observed with R² most of time above 0.85. Bland-Altman analysis showed a bias of 1.26% for Abbott i-STAT® System POCT vs laboratory.

Conclusion: Abbott i-STAT® System POCT handheld device is comparable to Radiometer ABL800 Flex® lab analyzer and concordant with laboratory analysis. Abbott i-STAT® System POCT handled device could be used in the prehospital settings in order to evaluate the severity of sepsis.

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雅培i-Stat®和Radiometer ABL 800 Flex®血气分析仪血气结果的比较对临床决策的影响

背景:需要护理点检测(POCT)来评估严重程度，并帮助在医院和院前进行分诊。在使用poct之前，必须将其分析性能与中心实验室参考方法进行比较。在本研究中，我们描述了雅培i-STAT®系统POCT手持设备和我院中心实验室血气分析仪所获得结果的可比性。方法:采用雅培i-STAT®系统POCT和Radiometer ABL800 Flex®实验室分析仪对37例重症监护病房(ICU)脓毒症患者的血液进行检测。研究参数为:pH、pO2、pCO2、碱过量(BE)、HCO3-和乳酸。采用Bland-Altman方法评价可比性。还评估了价值差异可能引起的不匹配的临床价值。结果:POCT结果与实验室分析仪结果的相关性较好，R²多数在0.85以上。Bland-Altman分析显示雅培i-STAT®系统POCT与实验室的偏差为1.26%。结论:雅培i-STAT®System POCT手持设备可与Radiometer ABL800 Flex®实验室分析仪相媲美，与实验室分析一致。雅培i-STAT®系统POCT处理设备可用于院前设置，以评估败血症的严重程度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annales de biologie clinique 医学-医学：研究与实验

CiteScore

0.80

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Multidisciplinary information with direct relevance to everyday practice Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation. With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.