{"title":"Polyphenols of Antibacterial Potential - May They Help in Resolving Some Present Hurdles in Medicine?","authors":"K Zapletal, G Machnik, B Okopień","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The phenomenon of antibiotic resistance has been recognized as one of the greatest threats to humanity. Therefore, there is an enormous need to introduce new antibiotics to the medical practice that will effectively eradicate the resistant bacterial strains threatening human health and life. One solution currently being considered as an alternative to antibiotics involves secondary metabolites of plants that can be used in modern antibacterial therapy. Polyphenols represent a broad and diversified group of plant-derived aromatic compounds. Their antibacterial potential has been recognized via specific mechanisms of action, e.g., by inhibition of bacterial biofilm formation, through synergistic effects with the action of currently used antibiotics, and by inhibition of the activity of bacterial virulence factors.</p>","PeriodicalId":12281,"journal":{"name":"Folia Biologica","volume":"68 3","pages":"87-96"},"PeriodicalIF":1.1000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia Biologica","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The phenomenon of antibiotic resistance has been recognized as one of the greatest threats to humanity. Therefore, there is an enormous need to introduce new antibiotics to the medical practice that will effectively eradicate the resistant bacterial strains threatening human health and life. One solution currently being considered as an alternative to antibiotics involves secondary metabolites of plants that can be used in modern antibacterial therapy. Polyphenols represent a broad and diversified group of plant-derived aromatic compounds. Their antibacterial potential has been recognized via specific mechanisms of action, e.g., by inhibition of bacterial biofilm formation, through synergistic effects with the action of currently used antibiotics, and by inhibition of the activity of bacterial virulence factors.
期刊介绍：
Journal of Cellular and Molecular Biology publishes articles describing original research aimed at the elucidation of a wide range of questions of biology and medicine at the cellular and molecular levels. Studies on all organisms as well as on human cells and tissues are welcome.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
