Undesired impact of iron supplement on MRI assessment of post-treatment glioblastoma.

Q1 Medicine
CNS Oncology Pub Date : 2022-12-01 DOI:10.2217/cns-2021-0018
Dahye Park, Mina Lobbous, Louis B Nabors, James M Markert, Jinsuh Kim
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引用次数: 1

Abstract

Glioblastoma (GBM) is the most common malignant adult brain and has a poor prognosis. Routine post-treatment MRI evaluations are required to assess treatment response and disease progression. We present a case of an 83-year-old female who underwent MRI assessment of post-treatment GBM after intravenous iron replacement therapy, ferumoxytol. The brain MRI revealed unintended alteration of MRI signal characteristics from the iron containing agent which confounded diagnostic interpretation and subsequently, the treatment planning. Ferumoxytol injection prior to contrast enhanced MRI must be screened in post-treatment GBM patients to accurately evaluate tumor activity.

Abstract Image

Abstract Image

Abstract Image

铁补充剂对治疗后胶质母细胞瘤MRI评估的不良影响。
胶质母细胞瘤(GBM)是成人脑部最常见的恶性肿瘤,预后较差。需要常规的治疗后MRI评估来评估治疗反应和疾病进展。我们报告了一例83岁的女性,她在静脉注射铁替代疗法阿魏木糖醇后接受了MRI评估治疗后的GBM。脑部MRI显示含铁剂的MRI信号特征发生意外改变,这混淆了诊断解释和随后的治疗计划。治疗后的GBM患者必须在造影增强MRI之前进行阿魏木醇注射筛查,以准确评估肿瘤活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CNS Oncology
CNS Oncology Medicine-Neurology (clinical)
CiteScore
3.80
自引率
0.00%
发文量
12
审稿时长
13 weeks
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