Nature, Nurture, and the Meaning of Educational Attainment: Differences by Sex and Socioeconomic Status.

IF 1 4区 医学 Q4 GENETICS & HEREDITY
Twin Research and Human Genetics Pub Date : 2023-02-01 Epub Date: 2023-03-13 DOI:10.1017/thg.2023.6
Thalida Em Arpawong, Margaret Gatz, Catalina Zavala, Tara L Gruenewald, Ellen E Walters, Carol A Prescott
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Abstract

Estimated heritability of educational attainment (EA) varies widely, from 23% to 80%, with growing evidence suggesting the degree to which genetic variation contributes to individual differences in EA is highly dependent upon situational factors. We aimed to decompose EA into influences attributable to genetic propensity and to environmental context and their interplay, while considering influences of rearing household economic status (HES) and sex. We use the Project Talent Twin and Sibling Study, drawn from the population-representative cohort of high school students assessed in 1960 and followed through 2014, to ages 68-72. Data from 3552 twins and siblings from 1741 families were analyzed using multilevel regression and multiple group structural equation models. Individuals from less-advantaged backgrounds had lower EA and less variation. Genetic variance accounted for 51% of the total variance, but within women and men, 40% and 58% of the total variance respectively. Men had stable genetic variance on EA across all HES strata, whereas high HES women showed the same level of genetic influence as men, and lower HES women had constrained genetic influence on EA. Unexpectedly, middle HES women showed the largest constraints in genetic influence on EA. Shared family environment appears to make an outsized contribution to greater variability for women in this middle stratum and whether they pursue more EA. Implications are that without considering early life opportunity, genetic studies on education may mischaracterize sex differences because education reflects different degrees of genetic and environmental influences for women and men.

Abstract Image

Abstract Image

自然、养育和教育成就的意义:性别和社会经济地位的差异。
教育程度(EA)的估计遗传力差异很大,从23%到80%不等,越来越多的证据表明,遗传变异对EA个体差异的影响程度在很大程度上取决于情境因素。我们的目的是将EA分解为可归因于遗传倾向、环境背景及其相互作用的影响,同时考虑养育家庭经济地位(HES)和性别的影响。我们使用了天才双胞胎和兄弟姐妹项目研究,该研究来自1960年评估的高中生群体代表性队列,并一直跟踪到2014年,年龄为68-72岁。采用多水平回归和多组结构方程模型对来自1741个家庭的3552对双胞胎和兄弟姐妹的数据进行了分析。来自弱势背景的个体的EA较低,变异较小。遗传变异占总变异的51%,但在女性和男性中,遗传变异分别占总方差的40%和58%。男性在所有HES阶层中对EA具有稳定的遗传变异,而高HES女性表现出与男性相同的遗传影响水平,低HES女性对EA的遗传影响有限。出乎意料的是,中等HES女性在遗传影响EA方面表现出最大的制约因素。共享的家庭环境似乎对这一中间阶层女性的可变性以及她们是否追求更多的EA做出了巨大贡献。其含义是,在不考虑早期生活机会的情况下,关于教育的基因研究可能会错误地描述性别差异,因为教育反映了女性和男性不同程度的基因和环境影响。
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来源期刊
Twin Research and Human Genetics
Twin Research and Human Genetics 医学-妇产科学
CiteScore
1.50
自引率
11.10%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.
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