Hemorrhagic Mass-Like Presentation of Vitreoretinal Lymphoma.

Pub Date : 2022-02-01 DOI:10.1159/000519300
Alessandro Marchese, Maria Vittoria Cicinelli, Francesco Bandello, Giulio Modorati, Elisabetta Miserocchi
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引用次数: 2

Abstract

Purpose: The aim of this study was to report the presentation, treatment, and outcomes of vitreoretinal lymphoma (VRL) associated with hemorrhagic mass-like lesions (HMLs) in the retina.

Methods: This study was a retrospective analysis of patients with HMLs associated with VRL seen at a single tertiary referral center. For each patient, the clinical charts, the fundus imaging, and the treatment outcomes were reviewed.

Results: Three eyes of 2 patients had VRL with HMLs. In all study eyes, HMLs were preceded by an area of retinitis-like retinal infiltration and evolved into elevated hemorrhagic masses. Two eyes had multiple relapses with HMLs. All HMLs regressed with treatment and were replaced by extensive chorioretinal atrophy.

Conclusion: VRL can present with HMLs. HMLs seem to correspond to massive intraretinal infiltration by VRL, mimicking a solid mass. Despite response to therapy, HMLs are associated with poor anatomical and functional outcomes.

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玻璃体视网膜淋巴瘤出血性肿块样表现。
目的:本研究的目的是报告与视网膜出血性肿块样病变(hml)相关的玻璃体视网膜淋巴瘤(VRL)的表现、治疗和结果。方法:本研究是对在单一三级转诊中心就诊的hml合并VRL患者的回顾性分析。对每位患者的临床图表、眼底成像和治疗结果进行了回顾。结果:2例患者3眼有VRL伴hml。在所有研究的眼睛中,hml之前都有视网膜炎样视网膜浸润区域,并演变为升高的出血性肿块。两只眼睛有多次复发的hml。所有hml均随治疗而消退,并被广泛的绒毛膜视网膜萎缩所取代。结论:VRL可合并hml。hml似乎对应于VRL的大量肠内浸润,类似于固体肿块。尽管对治疗有反应,但hml与解剖学和功能预后不良有关。
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