Long Story of Short Femur: A Single-Center Study with Step-Wise Imaging Approach.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Ultrasound Pub Date : 2024-09-01 Epub Date: 2023-01-10 DOI:10.1007/s40477-022-00765-1

Shubhra Agarwal, Arjit Agarwal, Shruti Chandak

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引用次数: 0

Abstract

Purpose: To evaluate the possible outcomes of fetuses diagnosed with short femur length (FL) and to guide diagnosis through a step-wise imaging algorithm.

Methods: This was a prospective cohort study of 42 pregnancies with fetal femur length (FL) below the 5th centile for gestational age. The cases were divided into two categories of isolated short FL & non-isolated short FL and followed up to determine the etiology.

Results: There were 11 cases of non-isolated short FL with skeletal dysplasia observed in 7 and chromosomal abnormalities in 4 cases. There were 31 cases with isolated short FL in which fetal growth restriction (FGR) occurred in 14/31 (45%) cases; 13 out of 31 (42%) were constitutional (short for gestational age, SGA) whereas 4/31(13%) showed normal interval growth on follow up (false positive).

Conclusion: Short femur can be isolated or non-isolated. Short femur length can be a good predictor and early sign of FGR. Serial follow up scan of the all cases of isolated short FL is important since a majority of them are normal and not require any further intervention. Cases of non-isolated short FL require step-wise approach to differentiate into dysplasia or aneuploidy.

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短股骨的漫长故事采用分步成像法的单中心研究

目的：评估被诊断为股骨长度（FL）过短的胎儿可能出现的结果，并通过分步成像算法指导诊断：这是一项前瞻性队列研究，研究对象为42例胎儿股骨长度（FL）低于胎龄第5百分位数的孕妇。这些病例被分为孤立性短股骨和非孤立性短股骨两类，并进行随访以确定病因：结果：非分离型短FL有11例，其中7例观察到骨骼发育不良，4例观察到染色体异常。31例中有13例（42%）胎儿生长受限（胎龄短，SGA），而4/31（13%）在随访中显示出正常的生长间隔（假阳性）：结论：股骨短小可以是孤立的，也可以是非孤立的。结论：股骨短小可分为孤立性和非孤立性两种，股骨短小可以很好地预测胎儿畸形。对所有孤立性短股骨的病例进行连续随访扫描非常重要，因为其中大多数病例都是正常的，不需要进一步干预。非孤立性短FL病例需要逐步区分发育不良或非整倍体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.10

自引率

15.00%

发文量

133

期刊介绍： The Journal of Ultrasound is the official journal of the Italian Society for Ultrasound in Medicine and Biology (SIUMB). The journal publishes original contributions (research and review articles, case reports, technical reports and letters to the editor) on significant advances in clinical diagnostic, interventional and therapeutic applications, clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and in cross-sectional diagnostic imaging. The official language of Journal of Ultrasound is English.

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