Identification of the novel HLA-DPA101:03:43 allele resulting from an intralocus recombination involving the DPA104:01:01:03 and DPA1*01:03:01:27 alleles sequenced by Next Generation Sequencing (NGS)

IF 2.3 4区医学 Q3 GENETICS & HEREDITY

International Journal of Immunogenetics Pub Date : 2022-11-07 DOI:10.1111/iji.12607

Turnbull Hannah, Brewin Gemma, Peacock Sarah

引用次数: 2

Abstract

HLA-DPA1 intralocus recombination between DPA1*04:01:01:03 and DPA1*01:03:01:27, or closely related other alleles, results in a novel allele HLA-DPA1*01:03:43.

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下一代测序技术(NGS)鉴定了DPA1*04:01:01:03和DPA1*01:03:01:27等位基因在基因座内重组后的HLA-DPA1*01:03:43等位基因

HLA-DPA1基因座内DPA1*04:01:01:03与DPA1*01:03:01:27或与之密切相关的其他等位基因进行重组，产生新的等位基因HLA-DPA1*01:03:43。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Immunogenetics 医学-免疫学

CiteScore

4.70

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The International Journal of Immunogenetics (formerly European Journal of Immunogenetics) publishes original contributions on the genetic control of components of the immune system and their interactions in both humans and experimental animals. The term ''genetic'' is taken in its broadest sense to include studies at the evolutionary, molecular, chromosomal functional and population levels in both health and disease. Examples are: -studies of blood groups and other surface antigens- cell interactions and immune response- receptors, antibodies, complement components and cytokines- polymorphism- evolution of the organisation, control and function of immune system components- anthropology and disease associations- the genetics of immune-related disease: allergy, autoimmunity, immunodeficiency and other immune pathologies- All papers are seen by at least two independent referees and only papers of the highest quality are accepted.

Identification of the novel HLA-DPA1*01:03:43 allele resulting from an intralocus recombination involving the DPA1*04:01:01:03 and DPA1*01:03:01:27 alleles sequenced by Next Generation Sequencing (NGS)

Abstract

Identification of the novel HLA-DPA101:03:43 allele resulting from an intralocus recombination involving the DPA104:01:01:03 and DPA1*01:03:01:27 alleles sequenced by Next Generation Sequencing (NGS)