ORGANOLEPTIC AND HALITOMETRIC ASSESSMENTS DO NOT CORRELATE WELL IN INTRA-ORAL HALITOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS

IF 4.1 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Eszter Szalai , Péter Tajti , Bence Szabó , Tamás Kói , Péter Hegyi , László Márk Czumbel , Gábor Varga , Beáta Kerémi
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引用次数: 0

Abstract

Background

The gold standard method for diagnosing oral halitosis is the subjective organoleptic measurement. Device-supported methods are also widespread worldwide. The challenges and safety concerns around performing organoleptic measurements during pandemics and the diversity of measuring device alternatives raised our clinical question: which halitometer is the most suitable for diagnosing halitosis?

Methods

This systematic review was registered in PROSPERO (ID CRD42022320024). The search was performed on March 23, 2022 in the following electronic databases: MEDLINE, Embase, Scopus, Web of Science, and CENTRAL. Adult populations with or without halitosis were included, and patients with systemic diseases were excluded. Organoleptic (subjective) measurement and the device-supported (objective) methods were compared; the primary outcome was the correlation coefficient, and the secondary was the specificity and sensitivity of the devices. QUADAS-2 and QUADAS-C were used to evaluate the risk of bias in the studies. Random–effects meta analyses were performed on the outcomes, and the secondary outcomes were plotted on a common ROC plot.

Results

A total of 1231 records were found in the 5 databases. After the selection process, 76 articles were eligible for the systematic review, and 14,635 patients were involved in the qualitative analysis. The pooled Spearman's correlation coefficient (c.c.) for sulfide monitors was 0.65; 95% CIs: [0.53-0.74]; I2 = 95%, P < .01. The pooled Spearman's c.c. for portable gas chromatographs was 0.69; 95% CIs: [0.63-0.74]; I2 = 12%, P < .01. The pooled Spearman's c.c. for gas chromatographs was 0.76; 95% CIs: [0.67-0.83]; I2 = 0%, P < .01.

Discussion

None of the most commonly used halitometers proved to be significantly superior to the others. Halimeter and OralChroma measurements did not correlate well with the organoleptic level of oral halitosis in adults. Therefore, better halitometers need to be developed as an alternative to organoleptic measurements.

器官感觉和口臭测量评估在器官内口臭中相关性不好:一项系统综述和荟萃分析。
背景:诊断口腔口臭的金标准方法是主观感官测量。设备支持的方法在世界范围内也很普遍。在流行病期间进行感官测量的挑战和安全问题以及测量设备替代品的多样性提出了我们的临床问题:哪种照度计最适合诊断口臭?方法:该系统综述在PROSPERO(ID CRD42022320024)中登记。搜索于2022年3月23日在以下电子数据库中进行:MEDLINE、Embase、Scopus、Web of Science和CENTRAL。包括有或没有口臭的成年人群,排除有系统性疾病的患者。比较了感官(主观)测量和设备支持(客观)方法;主要结果是相关系数,次要结果是装置的特异性和敏感性。QUADAS-2和QUADAS-C用于评估研究中的偏倚风险。对结果进行随机效应荟萃分析,并将次要结果绘制在通用ROC图上。结果:在5个数据库中共发现1231条记录。经过筛选过程,76篇文章符合系统综述的条件,14635名患者参与了定性分析。硫化物监测仪的Spearman相关系数(c.c.)为0.65;95%置信区间:[0.53-0.74];I2 = 95%,P<0.01。便携式气相色谱分析的Spearman系数为0.69;95%置信区间:[0.63-0.74];I2 = 12%,P<0.01。气相色谱法的合并Spearman系数为0.76;95%置信区间:[0.67-0.83];I2 = 0%,P<.01讨论:没有一种最常用的照度计被证明显著优于其他照度计。Halimeter和OralChroma测量与成人口腔口臭的感官水平没有很好的相关性。因此,需要开发更好的光度计作为感官测量的替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Evidence-Based Dental Practice
Journal of Evidence-Based Dental Practice DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
6.00
自引率
16.70%
发文量
105
审稿时长
28 days
期刊介绍: The Journal of Evidence-Based Dental Practice presents timely original articles, as well as reviews of articles on the results and outcomes of clinical procedures and treatment. The Journal advocates the use or rejection of a procedure based on solid, clinical evidence found in literature. The Journal''s dynamic operating principles are explicitness in process and objectives, publication of the highest-quality reviews and original articles, and an emphasis on objectivity.
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