Ethical challenges in research regarding aging population.

IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Mariane Lutz
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引用次数: 0

Abstract

Aging population is a global reality that forces public policies based on transdisciplinary research focused on older adults. This raises a series of issues, such as feasability, inequalities, inequities, vulnerability, access to the products generated, and ability to consent, among others. This essay's objective is to reflect on some of the questions that arise from this reality, review basic precepts of research ethics in human beings, and expose the challenges for updating the current guidelines for ethical biomedical research. Aged adults participating in clinical research should be respected, assured of an adequate risk/benefit balance, and selected fairly. The available guidelines generally recognize these basic principles, but they are not entirely guaranteed, as evidenced during the COVID-19 pandemic. This issue poses various ethical challenges and deserves to be considered in the guidelines and regulations for biomedical research with the participation of older adults.

人口老龄化研究中的伦理挑战。
人口老龄化是一个全球性的现实,迫使公共政策建立在以老年人为重点的跨学科研究的基础上。这引发了一系列问题,如可行性、不平等、不公平、脆弱性、获得所产生的产品以及同意的能力等。本文的目的是反思从这一现实中产生的一些问题,回顾人类研究伦理的基本原则,并揭示更新当前伦理生物医学研究指南的挑战。参与临床研究的老年人应该受到尊重,确保充分的风险/收益平衡,并公平地选择。现有的指导方针总体上承认了这些基本原则,但正如2019冠状病毒病大流行期间所证明的那样,这些原则并不能得到完全保证。这一问题提出了各种伦理挑战,值得在老年人参与的生物医学研究的指导方针和法规中加以考虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medwave
Medwave MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
8.30%
发文量
50
审稿时长
12 weeks
期刊介绍: Medwave is a peer-reviewed, biomedical and public health journal. Since its foundation in 2001 (Volume 1) it has always been an online only, open access publication that does not charge subscription or reader fees. Since January 2011 (Volume 11, Number 1), all articles are peer-reviewed. Without losing sight of the importance of evidence-based approach and methodological soundness, the journal accepts for publication articles that focus on providing updates for clinical practice, review and analysis articles on topics such as ethics, public health and health policy; clinical, social and economic health determinants; clinical and health research findings from all of the major disciplines of medicine, medical science and public health. The journal does not publish basic science manuscripts or experiments conducted on animals. Until March 2013, Medwave was publishing 11-12 numbers a year. Each issue would be posted on the homepage on day 1 of each month, except for Chile’s summer holiday when the issue would cover two months. Starting from April 2013, Medwave adopted the continuous mode of publication, which means that the copyedited accepted articles are posted on the journal’s homepage as they are ready. They are then collated in the respective issue and included in the Past Issues section.
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