Systemic chemotherapy for unresectable or recurrent primary thymic adenocarcinoma of enteric type.

IF 0.5 Q4 ONCOLOGY

International Cancer Conference Journal Pub Date : 2023-01-01 DOI:10.1007/s13691-022-00575-6

Xiaofang Gao

引用次数: 0

Abstract

Primary thymic adenocarcinoma of enteric type is a very rare subtype of thymic carcinoma. Choosing appropriate systemic chemotherapy for patients with unresectable or recurrent disease remain a big challenge. We present a case of 38-year-old man with primary thymic adenocarcinoma of enteric type. The patient received multiline chemotherapy. Metastatic lesions were effectively controlled by FOLFOX (oxaliplatin/5-fluorouracil/leucovorin) chemotherapy. According to the present case and the literature review, FOLFOX and XELOX (capecitabine/oxaliplatin) regimens are reasonable treatment choice for unresectable or recurrent primary thymic adenocarcinoma of enteric type, even in the first-line chemotherapy.

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不可切除或复发的肠型原发性胸腺癌的全身化疗。

肠型原发性胸腺癌是一种非常罕见的胸腺癌亚型。对于无法切除或复发的患者，选择合适的全身化疗仍然是一个巨大的挑战。我们报告一例38岁男性肠型原发性胸腺癌。患者接受了多线化疗。FOLFOX(奥沙利铂/5-氟尿嘧啶/亚叶酸钙)化疗有效控制转移灶。根据本病例和文献综述，对于不能切除或复发的肠型原发性胸腺癌，即使在一线化疗中，FOLFOX和XELOX(卡培他滨/奥沙利铂)方案也是合理的治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Cancer Conference Journal ONCOLOGY-

自引率

14.30%

发文量

期刊介绍： This online-only journal publishes original case reports on all types of cancer. In particular, we welcome not only case reports of educational value in the diagnosis and treatment of cancers, but also reports on molecularly analyzed cancer cases, including gene mutations, gene fusions, gene expression, and changes in copy number, regardless of their known clinical significance. Assessing the molecular analysis of a tumor usually requires a “cancer conference” in which experts from various fields discuss it. Even if the authors and their respective “cancer conference” were unable to determine the clinical significance of molecular changes at the time of submission and publication, their data may provide evidence that will help the scientific community develop precision medicine solutions in the future. We welcome case reports with reviews of the literature on similar cases, as they are more useful and valuable to readers than are reports of rare cases. International Cancer Conference Journal is the official publication of the Japan Society of Clinical Oncology (JSCO). - Presents an online-only collection of original case reports on all types of cancer - In particular, welcomes molecularly analyzed cancer cases - The Official Publication of the Japan Society of Clinical Oncology (JSCO)