Vault-Correlated Efficacy and Safety of Implantable Collamer Lens V4c Implantation for Myopia in Patients with Shallow Anterior Chamber Depth.

IF 2 4区医学 Q2 OPHTHALMOLOGY

Ophthalmic Research Pub Date : 2023-01-01 Epub Date: 2023-01-03 DOI:10.1159/000528616

Tianwei Qian, Jingxiao Du, Ruixia Ren, Hao Zhou, Haiyan Li, Zhihua Zhang, Xun Xu

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引用次数: 2

Abstract

Introduction: The aim of the study was to evaluate efficacy and safety outcomes after implantation of the Visian Implantable Collamer Lens (ICL V4c) in myopia patients with shallow anterior chamber depth (ACD).

Methods: This retrospective study followed 163 eyes of 94 patients for at least 24 months. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity, intraocular pressure (IOP), manifest refraction, vault, endothelial cell density (ECD), anterior chamber angle (ACA), anterior chamber volume, and the distance from the corneal endothelium to the central ICL (C-ICL) were measured during follow-ups. Spearman's correlation and logistic regression were used to identify variables correlated with changes in ECD and potential risk factors for ineffective outcomes, respectively.

Results: All surgeries were performed safely. High IOP of 9 eyes and anterior capsular opacity of 5 eyes were observed. The last follow-up ACA had a significant difference between the high and normal IOP groups (p = 0.0003). The mean ECD and vault were 2,855.76 ± 270.82 cells/mm2 and 388.01 ± 135.28 μm at the last follow-up, respectively. The vault and C-ICL were significantly associated with ΔECD (all p < 0.05). Furthermore, the vault was most responsible for the ECD loss. Twenty-two eyes had unsatisfactory postoperative UDVA, and the low vault at the last follow-up was a significant risk factor for this ineffective outcome (p < 0.001, OR = 14.739).

Conclusions: ICL V4c implantation in patients with shallow ACD achieved stable visual outcomes. The vault is related to postoperative visual acuity and ECD loss, which needs to be paid attention during follow-up.

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植入式科拉姆人工晶体 V4c 治疗前房深度较浅患者近视的 Vault 相关疗效和安全性。

导言：该研究旨在评估前房深度（ACD）较浅的近视患者植入 Visian 可植入角膜塑形镜（ICL V4c）后的疗效和安全性：这项回顾性研究对 94 名患者的 163 只眼睛进行了至少 24 个月的跟踪观察。随访期间测量了未矫正远视力 (UDVA)、矫正远视力、眼压 (IOP)、显性屈光度、穹窿、内皮细胞密度 (ECD)、前房角 (ACA)、前房容积以及角膜内皮到中央 ICL 的距离 (C-ICL)。斯皮尔曼相关性和逻辑回归分别用于确定与ECD变化相关的变量和无效结果的潜在风险因素：所有手术均安全进行。结果：所有手术均安全进行，9 只眼睛眼压偏高，5 只眼睛前囊混浊。最后一次随访的 ACA 在高眼压组和正常眼压组之间存在显著差异（P = 0.0003）。最后一次随访时，ECD 和穹隆的平均值分别为 2,855.76 ± 270.82 cells/mm2 和 388.01 ± 135.28 μm。穹隆和 C-ICL 与 ΔECD 显著相关（均为 p < 0.05）。此外，穹隆是造成 ECD 损失的主要原因。22只眼睛的术后UDVA不理想，最后一次随访时的低穹隆是导致这种无效结果的重要风险因素（p < 0.001，OR = 14.739）：结论：ICL V4c植入术在浅表ACD患者中取得了稳定的视觉效果。结论：ICL V4c 植入术在浅 ACD 患者中取得了稳定的视觉效果，但穹隆与术后视力和 ECD 损失有关，需要在随访过程中加以注意。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmic Research 医学-眼科学

CiteScore

3.80

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Ophthalmic Research'' features original papers and reviews reporting on translational and clinical studies. Authors from throughout the world cover research topics on every field in connection with physical, physiologic, pharmacological, biochemical and molecular biological aspects of ophthalmology. This journal also aims to provide a record of international clinical research for both researchers and clinicians in ophthalmology. Finally, the transfer of information from fundamental research to clinical research and clinical practice is particularly welcome.