De Novo Autoimmune Hepatitis after COVID-19 Infection in an Unvaccinated Patient.

Francisco A Durazo, Kelly Kristbaum, James Miller, Kia Saeian, Motaz Selim, Johnny C Hong
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引用次数: 5

Abstract

Liver test abnormalities have been described during severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection causing coronavirus disease 2019. Most of them consist of elevation of the aminotransferases that resolve once the infection subsides. There are several reports of autoimmune hepatitis developing after vaccination against COVID-19 and one case of autoimmune hepatitis following COVID-19 infection. We present a patient that was not vaccinated against COVID-19 and developed resistant de novo autoimmune hepatitis following COVID-19 infection requiring aggressive immunosuppression.

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未接种疫苗患者COVID-19感染后自身免疫性肝炎的发生
在严重急性呼吸综合征冠状病毒(SARS-CoV)-2感染导致2019冠状病毒病期间,有肝脏检查异常的描述。它们大多由转氨酶升高组成,一旦感染消退,转氨酶就会消失。有几例报道在接种COVID-19疫苗后发生自身免疫性肝炎,1例在COVID-19感染后发生自身免疫性肝炎。我们报告了一位未接种COVID-19疫苗的患者,在COVID-19感染后发展为耐药的自身免疫性肝炎,需要积极的免疫抑制。
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