Palliative profile, one-year mortality and quality of life in older inpatients according to Be-PICT: a multicenter prospective cohort study.

IF 1.6 4区 医学 Q2 Medicine
Isabelle De Brauwer, Séverine Henrard, Hilde Baeyens, Nele Van Den Noortgate, Marie De Saint-Hubert, Ruth Piers
{"title":"Palliative profile, one-year mortality and quality of life in older inpatients according to Be-PICT: a multicenter prospective cohort study.","authors":"Isabelle De Brauwer,&nbsp;Séverine Henrard,&nbsp;Hilde Baeyens,&nbsp;Nele Van Den Noortgate,&nbsp;Marie De Saint-Hubert,&nbsp;Ruth Piers","doi":"10.1080/17843286.2022.2053812","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>A palliative care approach (PCA), including advanced care planning (ACP), should be considered for patients with limited life expectancy. The Belgian Palliative Care Indicators Tool (Be-PICT) has been released to help identify patients who may benefit from such approach. This study aimed at measuring 1-year mortality and describe the quality of life in older inpatients, according to baseline Be-PICT results.</p><p><strong>Methods: </strong>Prospective multicentre cohort study in older patients (≥ 75 years) admitted at geriatrics and cardiology wards of four Belgian hospitals. The palliative profile was defined as a positive Be-PICT.1, defined by the presence of its three criteria, i.e. a negative physician's answer to the surprise question '<i>would you be surprised if this patient dies in the 6-12 next months?</i>', ≥ 1 poor health indicator and ≥ 1 life-limiting condition.</p><p><strong>Results: </strong>Of the 379 patients (50% aged ≥85 years; 51% female), 52 (14%) presented a palliative profile and 83 (23%) died within 1 year. Be-PICT.1 showed the following characteristics to predict 1-year mortality: sensitivity 0.54, specificity 0.83, positive and negative predictive values 0.48 and 0.86, positive and negative likelihood ratios 3.22 and 0.55. The patients with a palliative profile were at higher mortality risk (hazard ratio 4.79 p < 0.001) and 1-year mortality rate (45%). Not using the SQ allowed to improve sensitivity to include a larger number of patients who may benefit from ACP and PCA.</p><p><strong>Conclusions: </strong>Be-PICT.1 is a simple case-finding tool to identify older inpatients being at high mortality risk and candidates for ACP and PCA.</p>","PeriodicalId":7086,"journal":{"name":"Acta Clinica Belgica","volume":"78 1","pages":"16-24"},"PeriodicalIF":1.6000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Clinica Belgica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/17843286.2022.2053812","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Background: A palliative care approach (PCA), including advanced care planning (ACP), should be considered for patients with limited life expectancy. The Belgian Palliative Care Indicators Tool (Be-PICT) has been released to help identify patients who may benefit from such approach. This study aimed at measuring 1-year mortality and describe the quality of life in older inpatients, according to baseline Be-PICT results.

Methods: Prospective multicentre cohort study in older patients (≥ 75 years) admitted at geriatrics and cardiology wards of four Belgian hospitals. The palliative profile was defined as a positive Be-PICT.1, defined by the presence of its three criteria, i.e. a negative physician's answer to the surprise question 'would you be surprised if this patient dies in the 6-12 next months?', ≥ 1 poor health indicator and ≥ 1 life-limiting condition.

Results: Of the 379 patients (50% aged ≥85 years; 51% female), 52 (14%) presented a palliative profile and 83 (23%) died within 1 year. Be-PICT.1 showed the following characteristics to predict 1-year mortality: sensitivity 0.54, specificity 0.83, positive and negative predictive values 0.48 and 0.86, positive and negative likelihood ratios 3.22 and 0.55. The patients with a palliative profile were at higher mortality risk (hazard ratio 4.79 p < 0.001) and 1-year mortality rate (45%). Not using the SQ allowed to improve sensitivity to include a larger number of patients who may benefit from ACP and PCA.

Conclusions: Be-PICT.1 is a simple case-finding tool to identify older inpatients being at high mortality risk and candidates for ACP and PCA.

根据Be-PICT,老年住院患者的姑息性、一年死亡率和生活质量:一项多中心前瞻性队列研究
背景:对于预期寿命有限的患者,应考虑采用姑息治疗方法(PCA),包括高级护理计划(ACP)。比利时姑息治疗指标工具(Be-PICT)已经发布,以帮助确定可能从这种方法中受益的患者。本研究旨在测量1年死亡率,并根据基线Be-PICT结果描述老年住院患者的生活质量。方法:前瞻性多中心队列研究,纳入比利时四家医院老年病学和心脏病病房的老年患者(≥75岁)。姑息侧写定义为阳性的Be-PICT。1,由其存在的三个标准来定义,即一个消极的医生回答“如果这个病人在接下来的6-12个月内死亡,你会感到惊讶吗?”,健康不良指标≥1项,生命受限条件≥1项。结果:379例患者中(50%年龄≥85岁;51%为女性),52例(14%)表现出姑息性,83例(23%)在1年内死亡。Be-PICT。1显示以下特征预测1年死亡率:敏感性0.54,特异性0.83,阳性和阴性预测值分别为0.48和0.86,阳性和阴性似然比分别为3.22和0.55。采用姑息治疗的患者死亡风险较高(危险比4.79 p)。1是一种简单的病例查找工具,用于识别具有高死亡率风险的老年住院患者以及ACP和PCA的候选患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Acta Clinica Belgica
Acta Clinica Belgica 医学-医学:内科
CiteScore
2.90
自引率
0.00%
发文量
44
审稿时长
6-12 weeks
期刊介绍: Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine primarily publishes papers on clinical medicine, clinical chemistry, pathology and molecular biology, provided they describe results which contribute to our understanding of clinical problems or describe new methods applicable to clinical investigation. Readership includes physicians, pathologists, pharmacists and physicians working in non-academic and academic hospitals, practicing internal medicine and its subspecialties.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信