Mitotic Antipairing of Homologous Chromosomes.

Q4 Biochemistry, Genetics and Molecular Biology

Results and Problems in Cell Differentiation Pub Date : 2022-01-01 DOI:10.1007/978-3-031-06573-6_6

Lisa L Hua, Christian J Casas, Takashi Mikawa

引用次数: 0

Abstract

Chromosome organization is highly dynamic and plays an essential role during cell function. It was recently found that pairs of the homologous chromosomes are continuously separated at mitosis and display a haploid (1n) chromosome set, or "antipairing," organization in human cells. Here, we provide an introduction to the current knowledge of homologous antipairing in humans and its implications in human disease.

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同源染色体的有丝分裂反配对。

染色体组织是高度动态的，在细胞功能中起着至关重要的作用。最近发现，在人类细胞中，同源染色体对在有丝分裂时连续分离，并显示单倍体(1n)染色体组，或“反配对”组织。在这里，我们提供了一个介绍，目前的知识同源抗配对在人类和它的含义在人类疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Results and Problems in Cell Differentiation Biochemistry, Genetics and Molecular Biology-Developmental Biology

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Results and Problems in Cell Differentiation is an up-to-date book series that presents and explores selected questions of cell and developmental biology. Each volume focuses on a single, well-defined topic. Reviews address basic questions and phenomena, but also provide concise information on the most recent advances. Together, the volumes provide a valuable overview of this exciting and dynamically expanding field.