Comparison of outcomes between single long stent and overlapping stents: a meta-analysis of the literature.

IF 1.1 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Herz Pub Date : 2023-10-01 Epub Date: 2023-01-11 DOI:10.1007/s00059-022-05152-4

Faysal Şaylık, Tufan Çınar, Murat Selçuk, Vedat Çiçek, Mert Ilker Hayıroğlu, Ahmet Lütfullah Orhan

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引用次数: 5

Abstract

Objectives: There is no consensus on whether to treat diffuse coronary artery lesions with a single long stent (SLS) or by overlapping two or more stents (OLS). The goal of this review was to compare the outcomes of these two approaches through a meta-analysis of the literature.

Methods: We searched for relevant studies in MEDLINE, Scopus, EMBASE, Google Scholar, and the Cochrane Library. Our meta-analysis included 12 studies (n = 6414) that reported outcomes during the follow-up period.

Results: Individuals who received OLS had a greater risk of cardiac mortality and target lesion revascularization (TLR) than those who received SLS (RR: 1.51, CI: 1.03-2.21, p = 0.03, I² = 0% and RR: 1.64, CI: 1.02-2.65, p = 0.04, I² = 38%, respectively). The fluoroscopy period in the OLS group was longer than in the SLS group (SMD: 0.35, CI: 0.25-0.46, p < 0.01, I² = 0%). more contrast volume was sued for the OLS group; however, there was substantial variability in the pooled analysis (I² = 95%). In terms of all outcomes, there were no differences between stent generation types.

Conclusion: In the first meta-analysis of mainly observational data comparing OLS vs. SLS for long coronary lesions, OLS had higher rates of cardiac mortality and TLR as well as longer fluoroscopy times compared to SLS.

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单个长支架和重叠支架的疗效比较：一项文献荟萃分析。

目的：对于是用单个长支架（SLS）还是重叠两个或多个支架（OLS）治疗弥漫性冠状动脉病变，目前还没有达成共识。这篇综述的目的是通过对文献的荟萃分析来比较这两种方法的结果。方法：检索MEDLINE、Scopus、EMBASE、Google Scholar和Cochrane图书馆的相关研究。我们的荟萃分析包括12项研究（n = 6414）报告了随访期间的结果。结果：接受OLS的个体比接受SLS的个体有更大的心脏死亡率和靶病变血运重建（TLR）风险（RR:1.51，CI:1.03-2.21，p = 0.03，I2 = 0%，RR:1.64，CI:1.02-2.65，p = 0.04，I2 = 分别为38%）。OLS组的荧光透视时间长于SLS组（SMD:0.35，CI:0.25-0.46，p 2. = 0%）。OLS组的对比度更高；然而，在合并分析中存在显著的可变性（I2 = 95%）。就所有结果而言，支架生成类型之间没有差异。结论：在对OLS与SLS在长冠状动脉病变中的主要观察数据进行比较的第一次荟萃分析中，与SLS相比，OLS具有更高的心脏死亡率和TLR，以及更长的荧光检查时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Herz 医学-心血管系统

CiteScore

3.00

自引率

5.90%

发文量

审稿时长

4-8 weeks

期刊介绍： Herz is the high-level journal for further education for all physicians interested in cardiology. The individual issues of the journal each deal with specific topics and comprise review articles in English and German written by competent and esteemed authors. They provide up-to-date and comprehensive information concerning the speciality dealt with in the issue. Due to the fact that all relevant aspects of the pertinent topic of an issue are considered, an overview of the current status and progress in cardiology is presented. Reviews and original articles round off the spectrum of information provided.