The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies.

IF 1.9 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

International Journal of Hypertension Pub Date : 2022-01-01 DOI:10.1155/2022/4476905

Dingwei Liu, Chao Yu, Ke Huang, Shawn Thomas, Wei Yang, Song Liu, Jie Kuang

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引用次数: 2

Abstract

Background: Studies on bidirectional associations between hypertension and insomnia are inconclusive. The purpose of this meta-analysis was to systematically review and summarize the current evidence from epidemiological studies that evaluated this relationship.

Materials and methods: PubMed, Embase, China National Knowledge Infrastructure (CNKI), Wan Fang, and VIP databases were searched for studies published up to May 2021. Prospective cohort studies that reported the relationship between hypertension and insomnia in adults were included. Data were extracted or provided by the authors according to the prevalence rate, incidence rate, unadjusted or adjusted odds ratio (OR), and 95% confidence interval (CI). Heterogeneity was assessed by I2 statistics. ORs were pooled by using random-effects models.

Results: A total of 23 prospective studies were identified. Twenty cohort studies recorded OR-adjusted value with the outcome for hypertension (OR = 1.11, 95% CI: 1.07-1.16; I2 = 83.9%), and three cohort studies reported OR-adjusted value with the outcome for insomnia (OR = 1.20, 95%CI: 1.08-1.32; I2 = 35.1%). Subgroup analysis showed that early morning awakening and composite insomnia were significantly associated with hypertension.

Conclusions: The result indicates a possible bidirectional association between hypertension and insomnia. Early identification and prevention of insomnia in hypertension patients are needed, and vice versa.

Abstract Image

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高血压和失眠之间的关系:前瞻性队列研究的双向meta分析。

背景:关于高血压和失眠之间的双向关系的研究尚无定论。本荟萃分析的目的是系统地回顾和总结来自评估这种关系的流行病学研究的现有证据。材料和方法:检索PubMed、Embase、中国知网(CNKI)、万方和VIP数据库，检索截止到2021年5月发表的研究。报告成人高血压和失眠之间关系的前瞻性队列研究被纳入。数据由作者根据患病率、发病率、未调整或调整的优势比(or)和95%可信区间(CI)提取或提供。采用I2统计量评估异质性。使用随机效应模型汇总or。结果:共确定了23项前瞻性研究。20项队列研究记录了高血压结局的OR校正值(OR = 1.11, 95% CI: 1.07-1.16;I2 = 83.9%)，三个队列研究报告了失眠结局的OR校正值(OR = 1.20, 95%CI: 1.08-1.32;i2 = 35.1%)。亚组分析显示，早醒和复合失眠症与高血压有显著相关性。结论:高血压与失眠之间可能存在双向关联。高血压患者失眠需要早期识别和预防，反之亦然。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Hypertension Medicine-Internal Medicine

CiteScore

4.00

自引率

5.30%

发文量

期刊介绍： International Journal of Hypertension is a peer-reviewed, Open Access journal that provides a forum for clinicians and basic scientists interested in blood pressure regulation and pathophysiology, as well as treatment and prevention of hypertension. The journal publishes original research articles, review articles, and clinical studies on the etiology and risk factors of hypertension, with a special focus on vascular biology, epidemiology, pediatric hypertension, and hypertensive nephropathy.