Left atrial structure and function: association with blood pressure variability in pregnant women.

IF 1.2 4区医学 Q4 PERIPHERAL VASCULAR DISEASE

Blood Pressure Monitoring Pub Date : 2023-02-01 DOI:10.1097/MBP.0000000000000626

Selda Murat, Melih Velipasaoglu, Bektas Murat, Aytug Al, Sevil Cicek, Yüksel Cavusoglu

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引用次数: 0

Abstract

Background: The aim of this study was to investigate the relationship between left atrial (LA) abnormalities and ambulatory blood pressure variability (BPV) in pregnant women and their relationship with hypertension-related clinical outcomes in pregnancy.

Methods: This single-center, prospective study included 119 pregnant women. All participants underwent 24-h ambulatory blood pressure (BP) monitoring and echocardiographic examination before 20 weeks of gestation. BPV was evaluated using 24-h ambulatory BP monitoring. SD of the mean of SBP (SBP-SD) and DBP variability was calculated as 24-h, daytime and nighttime SBP and DBP. The patients were classified into two groups based on median 24-h SBP-SD (11.3 mmHg). LA features of the patients were compared according to the high and low BPV groups.

Results: One hundred and nineteen pregnant women (mean age, 28.6 ± 5.2 years) were included in the study. The mean office SBP and DBP were 108.7 ± 15.4 mmHg and 68.2 ± 10.2 mmHg, respectively. In pregnant women with high BPV, even though BP is normal, reservoir and conduit LA functions have decreased and LA stiffness has increased. Gestational hypertension and composite outcomes were more common in pregnant women with high BPV. Among the LA parameters, the most associated with composite outcome was conduit LA function.

Conclusion: In pregnancy, higher BPV is associated with worse LA function. The LA conduit strain offers potential value in predicting hypertension-related clinical outcomes in pregnancy.

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孕妇左房结构和功能与血压变异性的关系

背景:本研究的目的是探讨孕妇左房(LA)异常与动态血压变异性(BPV)的关系及其与妊娠期高血压相关临床结局的关系。方法:本研究为单中心前瞻性研究，纳入119名孕妇。所有参与者在妊娠20周前进行24小时动态血压监测和超声心动图检查。采用24小时动态血压监测评估BPV。收缩压(SBP-SD)和舒张压变异性均值的标准差计算为24小时、白天和夜间收缩压和舒张压。根据中位24小时SBP-SD (11.3 mmHg)将患者分为两组。根据高、低BPV组比较患者的LA特征。结果:共纳入孕妇119例，平均年龄28.6±5.2岁。平均办公室收缩压和舒张压分别为108.7±15.4 mmHg和68.2±10.2 mmHg。在高BPV的孕妇中，即使血压正常，储血池和导管LA功能下降，LA刚度增加。妊娠期高血压和复合结局在高BPV孕妇中更为常见。在LA参数中，与综合结果相关性最大的是导管LA功能。结论:妊娠期BPV升高与LA功能恶化相关。LA导管应变在预测妊娠期高血压相关临床结果方面具有潜在价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Blood Pressure Monitoring 医学-外周血管病

CiteScore

2.00

自引率

7.70%

发文量

110

审稿时长

>12 weeks

期刊介绍： Blood Pressure Monitoring is devoted to original research in blood pressure measurement and blood pressure variability. It includes device technology, analytical methodology of blood pressure over time and its variability, clinical trials - including, but not limited to, pharmacology - involving blood pressure monitoring, blood pressure reactivity, patient evaluation, and outcomes and effectiveness research. This innovative journal contains papers dealing with all aspects of manual, automated, and ambulatory monitoring. Basic and clinical science papers are considered although the emphasis is on clinical medicine. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.