Cristina Pizzimenti, Francesca Gianno, Marco Gessi
{"title":"Expanding the spectrum of \"mesenchymal\" tumors of the central nervous system.","authors":"Cristina Pizzimenti, Francesca Gianno, Marco Gessi","doi":"10.32074/1591-951X-826","DOIUrl":null,"url":null,"abstract":"<p><p>In this review, we summarize the clinical, histopathological, and molecular features of central nervous system (CNS) tumors with <i>BCOR</i> internal tandem duplication, intracranial mesenchymal tumor with <i>FET/CREB</i> fusion, CNS <i>CIC-</i>rearranged sarcomas and primary intracranial sarcoma <i>DICER1</i>-mutant, now included in the 2021 WHO classification of CNS tumors. Possible relationships between tumors occurring in the CNS and their systemic counterparts are discussed.</p>","PeriodicalId":45893,"journal":{"name":"PATHOLOGICA","volume":"114 6","pages":"455-464"},"PeriodicalIF":4.4000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/0c/pathol-2022-06-455.PMC9763981.pdf","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"PATHOLOGICA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32074/1591-951X-826","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 2
Abstract
In this review, we summarize the clinical, histopathological, and molecular features of central nervous system (CNS) tumors with BCOR internal tandem duplication, intracranial mesenchymal tumor with FET/CREB fusion, CNS CIC-rearranged sarcomas and primary intracranial sarcoma DICER1-mutant, now included in the 2021 WHO classification of CNS tumors. Possible relationships between tumors occurring in the CNS and their systemic counterparts are discussed.