The new bone WB-SPECT/CT: hybrid, from head-to-toe and digital! Is it worth the effort?

IF 2.9 3区 医学 Q3 ENGINEERING, BIOMEDICAL
Expert Review of Medical Devices Pub Date : 2023-07-01 Epub Date: 2023-08-29 DOI:10.1080/17434440.2023.2252743
Luca Filippi, Viviana Frantellizzi, Giuseppe De Vincentis, Orazio Schillaci
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引用次数: 1

Abstract

Introduction: A bone scan (BS) plays a pivotal role in many oncological and non-oncological conditions. The planar BS is characterized by high sensitivity but low specificity. With respect to planar imaging, the implementation of single-photon emission computed tomography (SPECT) has allowed increased image contrast and more accurate tracer localization.

Areas covered: Recent technological innovations in the field of BS are treated, with a particular focus on multi-field-of-view devices allowing to cover the entire scan length with a 3D acquisition (WB-SPECT/CT). In addition, the applications of cadmium zinc telluride/CzT detectors capable of converting gamma photons directly into electrical impulses (i.e. 'digital SPECT') are discussed.

Expert opinion: Initial clinical experiences indicate that WB-SPECT/CT is characterized by higher sensitivity, diagnostic accuracy, and increased confidence in image interpretation with respect to the 'old-fashioned' BS (planar images with or without a single field-of-view SPECT). Furthermore, CzT-based detectors, thanks to their superior sensitivity, might be helpful to implement fast acquisition protocols. Further studies are needed to better define the clinical impact of bone CzT WB-SPECT/CT on patients' management and outcome, as well as its cost-benefit ratio.

新骨WB-SPECT/CT:混合,从头到脚,数字化!这值得付出努力吗?
简介:骨扫描(BS)在许多肿瘤学和非肿瘤学疾病中起着关键作用。平面BS具有高灵敏度但低特异性的特点。关于平面成像,单光子发射计算机断层扫描(SPECT)的实现允许增加图像对比度和更准确的示踪剂定位。涵盖的领域:处理BS领域的最新技术创新,特别关注允许通过3D采集覆盖整个扫描长度的多视场设备(WB-SPECT/CT)。此外,还讨论了碲化镉锌/CzT探测器的应用,该探测器能够将伽马光子直接转换为电脉冲(即“数字SPECT”)。专家意见:初步临床经验表明,与“老式”BS(带或不带单视场SPECT的平面图像)相比,WB-SPECT/CT具有更高的灵敏度、诊断准确性和对图像解释的信心增加的特点。此外,基于CzT的检测器由于其优越的灵敏度,可能有助于实现快速采集协议。需要进一步的研究来更好地确定骨CzT WB-SPECT/CT对患者管理和结果的临床影响,以及其成本效益比。
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来源期刊
Expert Review of Medical Devices
Expert Review of Medical Devices 医学-工程:生物医学
CiteScore
5.90
自引率
3.20%
发文量
69
审稿时长
6-12 weeks
期刊介绍: The journal serves the device research community by providing a comprehensive body of high-quality information from leading experts, all subject to rigorous peer review. The Expert Review format is specially structured to optimize the value of the information to reader. Comprehensive coverage by each author in a key area of research or clinical practice is augmented by the following sections: Expert commentary - a personal view on the most effective or promising strategies Five-year view - a clear perspective of future prospects within a realistic timescale Key issues - an executive summary cutting to the author''s most critical points In addition to the Review program, each issue also features Medical Device Profiles - objective assessments of specific devices in development or clinical use to help inform clinical practice. There are also Perspectives - overviews highlighting areas of current debate and controversy, together with reports from the conference scene and invited Editorials.
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