Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population.

IF 1.4 4区医学 Q4 GERIATRICS & GERONTOLOGY

Experimental Aging Research Pub Date : 2024-01-01 Epub Date: 2022-12-22 DOI:10.1080/0361073X.2022.2160597

Majed Alotaibi, Melissa Lessard-Beaudoin, Kate Busch, Amal Loudghi, Pierrette Gaudreau, Rona K Graham

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引用次数: 0

Abstract

Background: In many neurological disorders, including Alzheimer disease, early olfactory dysfunction is observed.

Objective: In order to determine if deficits in olfactory memory are present in the elderly and if olfactory dysfunction correlates with cognitive impairment in the aging population, olfactory testing has been done on seniors from the NuAge cohort accepting to participate in the Olfactory Response Cognition and Aging (ORCA) secondary sub-study. The t-Mini Mental Statement Examination and the Telephone Interview for Cognitive Status tests were done to assess cognition levels.

Results: Overall, 94% of the ORCA cohort displayed olfactory dysfunction. Deficits in olfactory memory were also present. A correlation was observed between olfactory function and cognitive test scores. Moreover, in women who smoked, there was an association between olfactory memory and cognitive scores.

Conclusion: Our results suggest that olfactory dysfunction may predict impending cognitive decline and highlights the need for olfactory training in seniors to improve olfaction and overall well-being.

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与老年人认知能力下降有关的嗅觉功能障碍

背景：在包括阿尔茨海默病在内的许多神经系统疾病中，都能观察到早期嗅觉功能障碍：为了确定老年人是否存在嗅觉记忆缺陷，以及嗅觉功能障碍是否与老龄人口的认知障碍相关，我们对接受参加嗅觉反应认知与老龄化（ORCA）次级子研究的 NuAge 队列中的老年人进行了嗅觉测试。研究人员还进行了 t-Mini 心理陈述检查和认知状况电话访谈测试，以评估认知水平：结果：总体而言，ORCA 组群中有 94% 的人表现出嗅觉功能障碍。嗅觉记忆也存在缺陷。嗅觉功能与认知测试得分之间存在相关性。此外，在吸烟妇女中，嗅觉记忆与认知评分之间也存在关联：我们的研究结果表明，嗅觉功能障碍可能预示着认知能力即将衰退，并强调了对老年人进行嗅觉训练以改善嗅觉和整体健康的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Experimental Aging Research 医学-老年医学

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Experimental Aging Research is a life span developmental and aging journal dealing with research on the aging process from a psychological and psychobiological perspective. It meets the need for a scholarly journal with refereed scientific papers dealing with age differences and age changes at any point in the adult life span. Areas of major focus include experimental psychology, neuropsychology, psychobiology, work research, ergonomics, and behavioral medicine. Original research, book reviews, monographs, and papers covering special topics are published.