Infant Exposure to PCBs and PBDEs Revealed by Hair and Human Milk Analysis: Evaluation of Hair as an Alternative Biomatrix

IF 11.3 1区 环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL
Yuanjie Lin, Chao Feng, Sunyang Le, Xinlei Qiu, Qian Xu, Shuping Jin, Yamin Fang, Yu’e Jin, Yimin Wen, Guoquan Wang and Dasheng Lu*, 
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引用次数: 1

Abstract

Human hair, as an emerging biological monitoring matrix, has begun to be used in various human exposure studies, but little research has been done on persistent organic pollutants (POPs), especially for the body burden of POPs in infants. In this study, 36 breast-fed infants in Shanghai were recruited for a study to determine their exposure to POPs, including 12 dioxin-like polychlorinated biphenyls (dl-PCBs), 6 indicator PCBs, and 8 polybrominated diphenyl ethers (PBDEs) in the inner layer (internal) and outer layer (external) of infant hair and human milk. The similarity or difference of the POP distribution pattern or concentration among these matrices was investigated, and only weak correlations (r < 0.4) were observed between the POP concentration in human milk and infant hair (internal or external). POPs in human milk have a different profile than those in infant hair, while they have stable concentration ratios (0.58–2.72), similar distribution patterns, fine Spearman’s rank correlations, and tangled principal component analysis (PCA) plots in each POP family between external and internal hair samples. The result suggested that POPs in internal hair can be easily affected by those in external hair, but POPs in human milk seem to have little contribution to the POP profile in internal hair. Although infant hair cannot reflect the POPs from diet or from body burden, it can be an ideal biomatrix that estimates infant exposure to POPs from exogenous sources like house dust when considering the similar pattern of POPs and their proper accumulation period in hair.

Abstract Image

婴儿暴露于多氯联苯和多溴二苯醚的头发和人乳分析:评价头发作为一种替代生物基质
人类头发作为一种新兴的生物监测基质,已开始用于各种人体暴露研究,但对持久性有机污染物(POPs)的研究很少,特别是对婴儿持久性有机污染物的身体负担的研究很少。本研究在上海招募了36名母乳喂养的婴儿,研究了他们在婴儿头发和母乳的内层(内部)和外层(外部)中对持久性有机污染物的暴露情况,包括12种二恶英样多氯联苯(dl-PCBs), 6种指示性多氯联苯(PCBs)和8种多溴联苯醚(PBDEs)。研究了这些基质中POP分布模式或浓度的相似性或差异性,仅发现弱相关性(r <人乳中POP浓度与婴儿毛发(内部或外部)之间的差异为0.4)。人乳中持久性有机污染物与婴儿毛发中的持久性有机污染物具有不同的特征,但它们具有稳定的浓度比(0.58-2.72)、相似的分布模式、良好的Spearman 's秩相关性和缠结的主成分分析(PCA)图。结果表明,内发中的持久性有机污染物很容易受到外发中的持久性有机污染物的影响,但人乳中的持久性有机污染物似乎对内发中的持久性有机污染物的影响不大。虽然婴儿的头发不能反映来自饮食或身体负担的持久性有机污染物,但考虑到持久性有机污染物的相似模式及其在头发中的适当积累期,它可以是一个理想的生物基质,可以估计婴儿从房屋灰尘等外源性来源接触持久性有机污染物的情况。
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来源期刊
环境科学与技术
环境科学与技术 环境科学-工程:环境
CiteScore
17.50
自引率
9.60%
发文量
12359
审稿时长
2.8 months
期刊介绍: Environmental Science & Technology (ES&T) is a co-sponsored academic and technical magazine by the Hubei Provincial Environmental Protection Bureau and the Hubei Provincial Academy of Environmental Sciences. Environmental Science & Technology (ES&T) holds the status of Chinese core journals, scientific papers source journals of China, Chinese Science Citation Database source journals, and Chinese Academic Journal Comprehensive Evaluation Database source journals. This publication focuses on the academic field of environmental protection, featuring articles related to environmental protection and technical advancements.
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