The Resistance Training Effects on Skeletal Muscle Stem Cells in Older Adult: A Systematic Review and Meta-Analysis.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-08-01 DOI:10.22074/cellj.2023.1986679.1206

Diaco Heidari, Hossein Shirvani, Behzad Bazgir, Alireza Shamsoddini

{"title":"The Resistance Training Effects on Skeletal Muscle Stem Cells in Older Adult: A Systematic Review and Meta-Analysis.","authors":"Diaco Heidari, Hossein Shirvani, Behzad Bazgir, Alireza Shamsoddini","doi":"10.22074/cellj.2023.1986679.1206","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of this systematic review and meta-analysis is to examine the effects of resistance exercise training on muscle stem cells in older adults. A database search was performed (PubMed, Scopus, Web of Science and Google Scholar) to identify controlled clinical trials in English language. The mean difference (MD) with 95% confidence intervals (CIs) and overall effect size were calculated for all comparisons. The PEDro scale was used to assess the methodological quality. Nineteen studies were included in the review. The meta-analysis found a significant effect of resistance training (RT) on muscle stem cells in the elderly (difference in means=-0.008, Z=-3.415, P=0.001). Also, muscle stem cells changes were similar in men and women (difference in means=-0.004, Z=-1.558, P=0.119) and significant changes occur in type II muscle fibers (difference in means=-0.017, Z=-7.048, P=0.000). Resistance-type exercise training significantly increased muscle stem cells content in intervention group that this result is similar in men and womenthis increase occurred more in type II muscle fibers.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/bf/Cell-J-25-513.PMC10542207.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.22074/cellj.2023.1986679.1206","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

The objective of this systematic review and meta-analysis is to examine the effects of resistance exercise training on muscle stem cells in older adults. A database search was performed (PubMed, Scopus, Web of Science and Google Scholar) to identify controlled clinical trials in English language. The mean difference (MD) with 95% confidence intervals (CIs) and overall effect size were calculated for all comparisons. The PEDro scale was used to assess the methodological quality. Nineteen studies were included in the review. The meta-analysis found a significant effect of resistance training (RT) on muscle stem cells in the elderly (difference in means=-0.008, Z=-3.415, P=0.001). Also, muscle stem cells changes were similar in men and women (difference in means=-0.004, Z=-1.558, P=0.119) and significant changes occur in type II muscle fibers (difference in means=-0.017, Z=-7.048, P=0.000). Resistance-type exercise training significantly increased muscle stem cells content in intervention group that this result is similar in men and womenthis increase occurred more in type II muscle fibers.

Abstract Image

查看原文本刊更多论文

阻力训练对老年人骨骼肌干细胞的影响：系统综述和荟萃分析。

这项系统综述和荟萃分析的目的是检验阻力运动训练对老年人肌肉干细胞的影响。进行数据库搜索（PubMed、Scopus、Web of Science和Google Scholar），以确定英语对照临床试验。计算所有比较的平均差（MD）、95%置信区间（CI）和总体效应大小。PEDro量表用于评估方法学质量。19项研究被纳入审查。荟萃分析发现，阻力训练（RT）对老年人肌肉干细胞有显著影响（平均值差异=0.008，Z=-3.415，P=0.001），肌肉干细胞的变化在男性和女性中相似（平均值差异=0.004，Z=-1.558，P=0.019），II型肌纤维也发生了显著变化（平均值差值=0.017，Z=-7.048，P=0.000）。阻力型运动训练显著增加了干预组的肌肉干细胞含量，这一结果在男性和妇女中相似，这种增加在II型肌中发生得更多肌肉纤维。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.